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H2-M10.4 Gene Detail
Summary
  • Symbol
    H2-M10.4
  • Name
    histocompatibility 2, M region locus 10.4
  • Synonyms
    15H
  • Feature Type
    protein coding gene
  • IDs
    MGI:1276527
    NCBI Gene: 224753
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr17:36458917-36462329 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 19.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1276527
protein coding gene Chr17:36458917-36462334 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023676
protein coding gene Chr17:36823392-36826809 (-)
A/J MGP_AJ_G0023634
protein coding gene Chr17:35642883-35646300 (-)
AKR/J MGP_AKRJ_G0023605
protein coding gene Chr17:36044472-36047889 (-)
BALB/cJ MGP_BALBcJ_G0023641
protein coding gene Chr17:35842641-35846596 (-)
C3H/HeJ MGP_C3HHeJ_G0023403
protein coding gene Chr17:36586305-36589722 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024079
protein coding gene Chr17:38353049-38356906 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021551
protein coding gene Chr17:33485001-33488427 (-)
CAST/EiJ MGP_CASTEiJ_G0022890
protein coding gene Chr17:36623735-36627750 (-)
CBA/J MGP_CBAJ_G0023380
protein coding gene Chr17:39911060-39914477 (-)
DBA/2J MGP_DBA2J_G0023505
protein coding gene Chr17:35009521-35013888 (-)
FVB/NJ MGP_FVBNJ_G0023478
protein coding gene Chr17:34672393-34675810 (-)
LP/J MGP_LPJ_G0021591
protein coding gene Chr15:1680542-1683959 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023501
protein coding gene Chr17:38689117-38692534 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024125
protein coding gene Chr17:36353970-36358274 (-)
PWK/PhJ MGP_PWKPhJ_G0022642
protein coding gene Chr17:33808616-33812314 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 224753 NCBI Gene Model | MGI Sequence Detail 3413 C57BL/6J ±  kb
transcript NM_177634 RefSeq | MGI Sequence Detail 1448 C57BL/6  
polypeptide NP_808302 RefSeq | MGI Sequence Detail 331 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • PDB
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
less
  • All nucleic 4
    Genomic 3
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:45971 Arepalli SR, et al., Characterization of two class I genes from the H2-M region: evidence for a new subfamily. Immunogenetics. 1998;47(3):264-71
  • Latest
    J:207447 Leinders-Zufall T, et al., A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014 Apr 9;34(15):5121-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory