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Aqr Gene Detail
Summary
  • Symbol
    Aqr
  • Name
    aquarius
  • Synonyms
    mKIAA0560
  • Feature Type
    protein coding gene
  • IDs
    MGI:1276102
    NCBI Gene: 11834
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:114101161-114175339 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 57.57 cM, cytoband E5-F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    762 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1276102
 protein coding gene Chr2:114101161-114187024 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026302
 protein coding gene Chr2:116577825-116652783 (-)
A/J MGP_AJ_G0026263
 protein coding gene Chr2:111859798-111933896 (-)
AKR/J MGP_AKRJ_G0026242
 protein coding gene Chr2:114959266-115036743 (-)
BALB/cJ MGP_BALBcJ_G0026276
 protein coding gene Chr2:112074144-112148738 (-)
C3H/HeJ MGP_C3HHeJ_G0026021
 protein coding gene Chr2:115373617-115447967 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026723
 protein coding gene Chr2:120433472-120507313 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024103
 protein coding gene Chr2:107011512-107087729 (-)
CAST/EiJ MGP_CASTEiJ_G0025484
 protein coding gene Chr2:115678011-115755479 (-)
CBA/J MGP_CBAJ_G0025998
 protein coding gene Chr2:124653987-124729144 (-)
DBA/2J MGP_DBA2J_G0026137
 protein coding gene Chr2:111292111-111366359 (-)
FVB/NJ MGP_FVBNJ_G0026099
 protein coding gene Chr2:110154106-110230019 (-)
LP/J MGP_LPJ_G0026238
 protein coding gene Chr2:116884430-116959201 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026118
 protein coding gene Chr2:129033866-129109757 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026778
 protein coding gene Chr2:115025410-115100031 (-)
PWK/PhJ MGP_PWKPhJ_G0025220
 protein coding gene Chr2:110809657-110885880 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025019
 protein coding gene Chr2:114182287-114258805 (-)
WSB/EiJ MGP_WSBEiJ_G0025553
 protein coding gene Chr2:115846660-115923313 (-)



Homology
more
  • Human Ortholog
    AQR, aquarius intron-binding spliceosomal factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AQR, aquarius intron-binding spliceosomal factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    fSAP164, IBP160
  • Links
    NCBI Gene ID: 9716
    neXtProt AC: NX_O60306
    UniProt: O60306

  • Chr Location
    15q14; chr15:34856351-34969794 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 7629
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: AQR
  • Protein SuperFamily
    AQR_cwf11
  • Gene Tree
    Aqr
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Homozygotes for a targeted null mutation exhibit severe defects in placental vascularization with few vessels entering the placenta and little branching. Mutants die between embryonic days 9.5 and 10.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    177
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11834 NCBI Gene Model | MGI Sequence Detail 74179 C57BL/6J ±  kb
transcript NM_009702 RefSeq | MGI Sequence Detail 4897 C57BL/6  
polypeptide Q8CFQ3 UniProt | EBI | MGI Sequence Detail 1481 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 182
    Genomic 1
    cDNA 181

    Microarray probesets 9
Other
Accession IDs
less
MGI:2139359
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory