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Taldo1 Gene Detail
Summary
  • Symbol
    Taldo1
  • Name
    transaldolase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1274789
    NCBI Gene: 21351
  • Gene Overview
    MyGene.info: TALDO1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141392199-141402968 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 86.73 cM, cytoband F3-F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1274789
protein coding gene Chr7:141392160-141402976 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033226
protein coding gene Chr7:146578832-146590245 (+)
A/J MGP_AJ_G0033208
protein coding gene Chr7:142385548-142396283 (+)
AKR/J MGP_AKRJ_G0033140
protein coding gene Chr7:146318989-146332295 (+)
BALB/cJ MGP_BALBcJ_G0033209
protein coding gene Chr7:142131039-142142379 (+)
C3H/HeJ MGP_C3HHeJ_G0032923
protein coding gene Chr7:146076639-146087511 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033720
protein coding gene Chr7:151930208-151942087 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030693
protein coding gene Chr7:143600678-143611074 (+)
CAST/EiJ MGP_CASTEiJ_G0032253
protein coding gene Chr7:138384450-138396842 (+)
CBA/J MGP_CBAJ_G0032895
protein coding gene Chr7:157087145-157097943 (+)
DBA/2J MGP_DBA2J_G0033047
protein coding gene Chr7:140333739-140345297 (+)
FVB/NJ MGP_FVBNJ_G0033000
protein coding gene Chr7:140248399-140260478 (+)
LP/J MGP_LPJ_G0033142
protein coding gene Chr7:148075561-148086996 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033033
protein coding gene Chr7:157725233-157736746 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033740
protein coding gene Chr7:145292242-145303677 (+)
PWK/PhJ MGP_PWKPhJ_G0031957
protein coding gene Chr7:133615175-133627041 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031804
protein coding gene Chr7:132116569-132136269 (+)
WSB/EiJ MGP_WSBEiJ_G0032364
protein coding gene Chr7:146240845-146252745 (+)



Homology
more
  • Human Ortholog
    TALDO1, transaldolase 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TALDO1, transaldolase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TAL, TALDOR, TALH, TAL-H
  • Links
    NCBI Gene ID: 6888
    neXtProt AC: NX_P37837
    UniProt: P37837

  • Chr Location
    11p15.5; chr11:747432-765024 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in male infertility due to defective sperm motility because of functional and structural defects of mitochondria in the sperm. Heterozygous mice show reduced male fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025503 Ensembl Gene Model | MGI Sequence Detail 10770 C57BL/6J ±  kb
    transcript ENSMUST00000211654 Ensembl | MGI Sequence Detail 1362 Not Applicable  
    polypeptide ENSMUSP00000147332 Ensembl | MGI Sequence Detail 382 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 400
      cDNA 400

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:47229 Kusuda J, et al., Cloning and chromosomal localization of a paralog and a mouse homolog of the human transaldolase gene. Gene. 1998 Mar 16;209(1-2):13-21
    • Latest
      J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory