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Taldo1
Gene Detail
 Symbol
Name
ID
Taldo1
transaldolase 1
MGI:1274789
Feature Type protein coding gene
Genetic Map
Chromosome 7
86.73 cM, cytoband F3-F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:141392199-141402968 bp, + strand
From VEGA annotation of GRCm38

  10770 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4916  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: transaldolase
Gene Tree: Taldo1

Human
homologs
Human Homolog TALDO1, transaldolase 1
NCBI Gene ID 6888
neXtProt AC  NX_P37837
Human Synonyms  TAL, TALDOR, TALH, TAL-H
Human Chr (Location)  11p15.5-p15.4; chr11:747432-765024 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TALDO1
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
 
Homozygous mutation of this gene results in male infertility due to defective sperm motility because of functional and structural defects of mitochondria in the sperm. Heterozygous mice show reduced male fertility.
 
Interactions
Taldo1 interacts with 33 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process carbohydrate metabolic process, fructose 6-phosphate metabolic process, ...
Component cytoplasm, cytosol, ...
Function carbohydrate binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (14)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(399)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(399) cDNA(399)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027257 (Evidence)
Ensembl Gene ModelENSMUSG00000025503 (Evidence)
Entrez Gene21351 (Evidence)
UniGene29182
DFCITC1573334
DoTSDT.537679, DT.94377099, DT.97415341
NIA Mouse Gene IndexU008958, U125281
EC2.2.1.2
PDB2CWN, 2E1D
Consensus CDS ProjectCCDS22011.1
International Mouse Knockout Project StatusTaldo1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027257 VEGA Gene Model | MGI Sequence Detail 10770 C57BL/6J ±  kb
transcript OTTMUST00000067396 VEGA | MGI Sequence Detail 1229 Not Applicable 
polypeptide OTTMUSP00000033905 VEGA | MGI Sequence Detail 337 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(128 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013785 Aldolase-type TIM barrel
InterPro IPR001585 Transaldolase
InterPro IPR018225 Transaldolase, active site
InterPro IPR004730 Transaldolase type 1
Protein Ontology PR:000016045 transaldolase
References (Earliest) J:47229 Kusuda J, et al., Cloning and chromosomal localization of a paralog and a mouse homolog of the human transaldolase gene. Gene. 1998 Mar 16;209(1-2):13-21
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory