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Prss40
Gene Detail
 Symbol
Name
ID
Prss40
protease, serine 40
MGI:1270857
Synonyms Tesp2
Feature Type protein coding gene
Genetic Map
Chromosome 1
13.34 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:34543975-34560943 bp, - strand
From VEGA annotation of GRCm38

  16969 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69043  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Prss40

Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process proteolysis
Component cytoplasmic vesicle, extracellular region
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022629 (Evidence)
Ensembl Gene ModelENSMUSG00000037529 (Evidence)
Entrez Gene21756 (Evidence)
NIA Mouse Gene IndexU021219
EC3.4.21.-
Consensus CDS ProjectCCDS14870.1
International Mouse Knockout Project StatusPrss40
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022629 VEGA Gene Model | MGI Sequence Detail 16969 C57BL/6J ±  kb
transcript OTTMUST00000054210 VEGA | MGI Sequence Detail 1275 Not Applicable 
polypeptide OTTMUSP00000025842 VEGA | MGI Sequence Detail 365 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(16) UniProt(4)
Polymorphisms SNPs within 2kb(387 from dbSNP Build 137)    SNPs within 2kb including multiple locations(397)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016919 testicular serine protease 2
References (Earliest) J:47342 Kohno N, et al., Two novel testicular serine proteases, TESP1 and TESP2, are present in the mouse sperm acrosome. Biochem Biophys Res Commun. 1998 Apr 28;245(3):658-65
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory