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Prss40
Gene Detail
Symbol

Name
ID
Prss40
protease, serine 40
MGI:1270857
Synonyms
Tesp2
Feature Type
protein coding gene
Genetic Map
Chromosome 1
13.34 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:34543975-34560943 bp, - strand
From VEGA annotation of GRCm38

  16969 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69043  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Prss40

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss40 interacts with 117 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process proteolysis
Component cytoplasmic vesicle, extracellular region
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022629 (Evidence)
Ensembl Gene ModelENSMUSG00000037529 (Evidence)
Entrez Gene21756 (Evidence)
NIA Mouse Gene IndexU021219
EC3.4.21.-
Consensus CDS ProjectCCDS14870.1
International Mouse Knockout Project StatusPrss40
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022629 VEGA Gene Model | MGI Sequence Detail 16969 C57BL/6J ±  kb
transcript OTTMUST00000054210 VEGA | MGI Sequence Detail 1275 Not Applicable 
polypeptide OTTMUSP00000025842 VEGA | MGI Sequence Detail 365 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(16) UniProt(4)
Polymorphisms
SNPs within 2kb(387 from dbSNP Build 137)    SNPs within 2kb including multiple locations(397)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016919 testicular serine protease 2
References
(Earliest) J:47342 Kohno N, et al., Two novel testicular serine proteases, TESP1 and TESP2, are present in the mouse sperm acrosome. Biochem Biophys Res Commun. 1998 Apr 28;245(3):658-65
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory