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Prss40 Gene Detail
Summary
  • Symbol
    Prss40
  • Name
    protease, serine 40
  • Synonyms
    Tesp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270857
    NCBI Gene: 21756
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:34543968-34560943 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 13.34 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    418 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270857
protein coding gene Chr1:34536515-34560995 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015912
protein coding gene Chr1:32941829-32966817 (-)
A/J MGP_AJ_G0015896
protein coding gene Chr1:32148309-32165847 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0015850
protein coding gene Chr1:31820621-31831928 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0016303
protein coding gene Chr1:34453896-34473510 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014025
protein coding gene Chr1:29316238-29324352 (-)
CAST/EiJ MGP_CASTEiJ_G0015264
protein coding gene Chr1:32630318-32637538 (-)
CBA/J MGP_CBAJ_G0015655
protein coding gene Chr1:35424013-35444282 (-)
DBA/2J MGP_DBA2J_G0015756
protein coding gene Chr1:31486565-31505582 (-)
FVB/NJ MGP_FVBNJ_G0015758
protein coding gene Chr1:31034551-31054221 (-)
LP/J MGP_LPJ_G0015826
protein coding gene Chr1:33288157-33309221 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015778
protein coding gene Chr1:37664329-37685105 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016350
protein coding gene Chr1:32543029-32567528 (-)
PWK/PhJ MGP_PWKPhJ_G0015047
protein coding gene Chr1:31230942-31239450 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014828
protein coding gene Chr1:32533995-32542458 (-)
WSB/EiJ MGP_WSBEiJ_G0015326
protein coding gene Chr1:32534776-32558645 (-)



Homology
more
  • Human Ortholog
    PRSS40A, serine protease 40A (pseudogene)
  • Vertebrate Orthologs
    2
  • Human Ortholog
    PRSS40A, serine protease 40A (pseudogene)
    Orthology source: HGNC
  • Synonyms
    TISP43
  • Links
    NCBI Gene ID: 150527

  • Chr Location
    2q21.1; chr2:130570846-130584161 (+)  GRCh38.p7

  • Human Ortholog
    PRSS40B, serine protease 40B (pseudogene)
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 646743

  • Chr Location
    2q21.1; chr2:130536570-130549915 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037529 Ensembl Gene Model | MGI Sequence Detail 16976 C57BL/6J ±  kb
transcript ENSMUST00000047840 Ensembl | MGI Sequence Detail 1275 Not Applicable  
polypeptide ENSMUSP00000045118 Ensembl | MGI Sequence Detail 365 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:47342 Kohno N, et al., Two novel testicular serine proteases, TESP1 and TESP2, are present in the mouse sperm acrosome. Biochem Biophys Res Commun. 1998 Apr 28;245(3):658-65
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory