Prss40
Gene Detail

Symbol Name ID

Prss40 protease, serine, 40 MGI:1270857

Synonyms

Tesp2

Feature Type

protein coding gene

Genetic Map

Chromosome 1

13.34 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:34543975-34560943 bp, - strand From VEGA annotation of GRCm38   16969 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:69043  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Prss40

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	proteolysis
Component	cytoplasmic vesicle, extracellular region
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(6) cDNA(6)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000022629 (Evidence)
Ensembl Gene Model	ENSMUSG00000037529 (Evidence)
Entrez Gene	21756 (Evidence)
NIA Mouse Gene Index	U021219
EC	3.4.21.-
Consensus CDS Project	CCDS14870.1
International Mouse Knockout Project Status	Prss40

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022629	VEGA Gene Model | MGI Sequence Detail	16969	C57BL/6J
transcript	OTTMUST00000054210	VEGA | MGI Sequence Detail	1275	Not Applicable
polypeptide	OTTMUSP00000025842	VEGA | MGI Sequence Detail	365	Not Applicable

All sequences(24) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(239 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000016919	testicular serine protease 2

References

(Earliest) J:47342 Kohno N, et al., Two novel testicular serine proteases, TESP1 and TESP2, are present in the mouse sperm acrosome. Biochem Biophys Res Commun. 1998 Apr 28;245(3):658-65
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)