About   Help   FAQ
Prss39
Gene Detail
 Symbol
Name
ID
Prss39
protease, serine 39
MGI:1270856
Synonyms Tesp1
Feature Type protein coding gene
Genetic Map
Chromosome 1
13.29 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:34498410-34503063 bp, + strand
From VEGA annotation of GRCm38

  4654 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84781  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Protein SuperFamily: trypsin
Gene Tree: Prss39

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss39 interacts with 20 markers (Mir325, Mir342, Mir344, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process proteolysis
Component cytoplasmic vesicle, extracellular region
Function catalytic activity, serine-type endopeptidase activity
External Resources: FuncBase
Expression
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000049474 (Evidence)
Ensembl Gene ModelENSMUSG00000026125 (Evidence)
Entrez Gene21755 (Evidence)
UniGene10725
DFCITC1585544
DoTSDT.50315469
NIA Mouse Gene IndexU000143
Consensus CDS ProjectCCDS14868.1
International Mouse Knockout Project StatusPrss39
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049474 VEGA Gene Model | MGI Sequence Detail 4654 C57BL/6J ±  kb
transcript OTTMUST00000126123 VEGA | MGI Sequence Detail 1267 Not Applicable 
polypeptide OTTMUSP00000068255 VEGA | MGI Sequence Detail 367 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(154 from dbSNP Build 137)    SNPs within 2kb including multiple locations(164)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016918 inactive testicular serine protease 1
References (Earliest) J:47342 Kohno N, et al., Two novel testicular serine proteases, TESP1 and TESP2, are present in the mouse sperm acrosome. Biochem Biophys Res Commun. 1998 Apr 28;245(3):658-65
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory