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Cacybp
Gene Detail
Symbol

Name
ID
Cacybp
calcyclin binding protein
MGI:1270839
Feature Type
protein coding gene
Genetic Map
Chromosome 1
69.61 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:160202367-160212892 bp, - strand
From NCBI annotation of GRCm38

  10526 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7649  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cacybp

Human
homologs
Human Homolog CACYBP, calcyclin binding protein
NCBI Gene ID 27101
neXtProt AC  NX_Q9HB71
Human Synonyms  GIG5, S100A6BP, SIP
Human Chr (Location)  1q24-q25; chr1:174999435-175012027 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(159) : Gene trapped(155) Targeted(4)
 
Mice homozygous for a null allele exhibit reduced thymus and spleen cellularity, and defects in TCR-rearrangement.
 
Interactions
Cacybp interacts with 203 markers (Mir7-1, Mir16-1, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (272)    Tissues (42)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 272
cDNA source data(114)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(114) cDNA(114)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000014226 (Evidence)
Entrez Gene12301 (Evidence)
UniGene10702
DFCITC1611802, TC1572969
DoTSDT.492840
NIA Mouse Gene IndexU284488, U021948
PDB1YSM, 2JTT
Consensus CDS ProjectCCDS15406.1
International Mouse Knockout Project StatusCacybp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12301 NCBI Gene Model | MGI Sequence Detail 10526 C57BL/6J ±  kb
transcript NM_009786 RefSeq | MGI Sequence Detail 2115 C57BL/6 
polypeptide Q9CXW3 UniProt | EBI | MGI Sequence Detail 229 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007052 CS-like domain
InterPro IPR008978 HSP20-like chaperone
InterPro IPR007699 SGS
InterPro IPR015120 Siah interacting protein, N-terminal
Protein Ontology PR:000004958 calcyclin-binding protein
Graphical View of Protein Domain Structure
References
(Earliest) J:47153 Filipek A, et al., Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin. J Neurochem. 1998 May;70(5):1793-8
(Latest) J:199055 Jurewicz E, et al., CacyBP/SIP as a novel modulator of the thin filament. Biochim Biophys Acta. 2013 Mar;1833(3):761-6
All references(45)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory