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Cacybp
Gene Detail
Symbol

Name
ID
Cacybp
calcyclin binding protein
MGI:1270839
Feature Type
protein coding gene
Genetic Map
Chromosome 1
69.61 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:160202367-160212875 bp, - strand
From VEGA annotation of GRCm38

  10509 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7649  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CACYBP
Gene Tree: Cacybp

Human
homologs
CACYBP, calcyclin binding protein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 27101
neXtProt AC: NX_Q9HB71

Human Synonyms: GIG5, PNAS-107, S100A6BP, SIP

Human Chr (Location): 1q24-q25; chr1:174999435-175012027 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(160) : Gene trapped(155) Targeted(5)
 
Mice homozygous for a null allele exhibit reduced thymus and spleen cellularity, and defects in TCR-rearrangement.
 
Interactions
Cacybp interacts with 203 markers (Mir7-1, Mir16-1, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (272)    Tissues (42)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 272
cDNA source data(114)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cacybp ; ZFIN cacybp    NEW 
Molecular
reagents
All nucleic(114) cDNA(114)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000050680 (Evidence)
Ensembl Gene Model ENSMUSG00000014226 (Evidence)
Entrez Gene 12301 (Evidence)
UniGene 10702
DFCI TC1572969, TC1611802
DoTS DT.492840
NIA Mouse Gene Index U021948, U284488
PDB 2JTT, 1YSM
Consensus CDS Project CCDS15406.1
International Mouse Phenotyping Consortium Status Cacybp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050680 VEGA Gene Model | MGI Sequence Detail 10509 C57BL/6J ±  kb
transcript OTTMUST00000128481 VEGA | MGI Sequence Detail 2098 Not Applicable 
polypeptide OTTMUSP00000069117 VEGA | MGI Sequence Detail 229 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007052 CS-like domain
InterPro IPR008978 HSP20-like chaperone
InterPro IPR007699 SGS
InterPro IPR015120 Siah interacting protein, N-terminal
Protein Ontology PR:000004958 calcyclin-binding protein
References
(Earliest) J:47153 Filipek A, et al., Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin. J Neurochem. 1998 May;70(5):1793-8
(Latest) J:220406 Ishihara K, et al., Comparative proteomic profiling reveals aberrant cell proliferation in the brain of embryonic Ts1Cje, a mouse model of Down syndrome. Neuroscience. 2014 Sep 28;281C:1-15
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory