Sept4
Gene Detail

Symbol Name ID

Sept4 septin 4 MGI:1270156

Synonyms

Bh5, cell division control-related protein 2b, Pnutl2, septin H5

Feature Type

protein coding gene

Genetic Map

Chromosome 11

52.14 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr11:87568903-87590539 bp, + strand From VEGA annotation of GRCm38   21637 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:6107  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept4

Human homologs

Human Homolog		SEPT4, septin 4
NCBI Gene ID		5414
neXtProt AC		NX_O43236
Human Synonyms		ARTS, BRADEION, CE5B3, H5, hCDCREL-2, MART, PNUTL2, SEP4
Human Chr (Location)		17q22; chr17:56597611-56618179 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Homozygous null males are sterile and have immotile and structurally defective sperm that is bent and lacks the annulus.

 

Gene Ontology (GO) classifications

All GO classifications: (20 annotations)

Process	brain development, cell cycle, ...
Component	cell projection, cytoplasm, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (79)    Tissues (50)    Images (27)
Theiler Stages: 19, 23, 24, 28

Assay Type	Results
RNA in situ	79

cDNA source data(58)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(59) cDNA(59)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000001264 (Evidence)
Ensembl Gene Model	ENSMUSG00000020486 (Evidence)
Entrez Gene	18952 (Evidence)
UniGene	2214
DFCI	TC1576476, TC1587750, TC1605841, TC1690656
DoTS	DT.101386318, DT.101386322, DT.110546065, DT.481763, DT.91428473, DT.94204926, DT.94204936, DT.97394479
NIA Mouse Gene Index	U013140
Consensus CDS Project	CCDS25213.1
International Mouse Knockout Project Status	Sept4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000001264	VEGA Gene Model | MGI Sequence Detail	21637	C57BL/6J
transcript	OTTMUST00000002519	VEGA | MGI Sequence Detail	1726	Not Applicable
polypeptide	OTTMUSP00000001240	VEGA | MGI Sequence Detail	478	Not Applicable

All sequences(84) RefSeq(2) UniProt(4)

Protein-related information

Resource	ID	Description
InterPro	IPR000038	Cell division protein GTP binding
InterPro	IPR016491	Septin
Protein Ontology	PR:000014656	septin-4

References

(Earliest) J:15086 Kato K, A collection of cDNA clones with specific expression patterns in mouse brain. Eur J Neurosci. 1990;2(8):704-11
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(46)