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Reep5 Gene Detail
Summary
  • Symbol
    Reep5
  • Name
    receptor accessory protein 5
  • Synonyms
    Dp1, DP1/TB2, TB2/DP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270152
    NCBI Gene: 13476
  • Gene Overview
    MyGene.info: REEP5
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34344889-34373415 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 18.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    124 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270152
protein coding gene Chr18:34344885-34373415 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024238
protein coding gene Chr18:32545297-32575165 (-)
A/J MGP_AJ_G0024204
protein coding gene Chr18:31452360-31480879 (-)
AKR/J MGP_AKRJ_G0024173
protein coding gene Chr18:32344450-32372930 (-)
BALB/cJ MGP_BALBcJ_G0024204
protein coding gene Chr18:31517025-31545520 (-)
C3H/HeJ MGP_C3HHeJ_G0023972
protein coding gene Chr18:32366762-32395207 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024646
protein coding gene Chr18:33783468-33811975 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022087
protein coding gene Chr18:31598534-31626653 (-)
CAST/EiJ MGP_CASTEiJ_G0023447
protein coding gene Chr18:32303853-32335455 (-)
CBA/J MGP_CBAJ_G0023940
protein coding gene Chr18:34714574-34745868 (-)
DBA/2J MGP_DBA2J_G0024072
protein coding gene Chr18:31114916-31143358 (-)
FVB/NJ MGP_FVBNJ_G0024038
protein coding gene Chr18:30801612-30830364 (-)
LP/J MGP_LPJ_G0024153
protein coding gene Chr18:32631995-32660544 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024066
protein coding gene Chr18:36011950-36040499 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024694
protein coding gene Chr18:32171986-32201262 (-)
PWK/PhJ MGP_PWKPhJ_G0023190
protein coding gene Chr18:31299857-31328743 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022999
protein coding gene Chr18:32441101-32468879 (-)
WSB/EiJ MGP_WSBEiJ_G0023510
protein coding gene Chr18:32097364-32127784 (-)



Homology
more
  • Human Ortholog
    REEP5, receptor accessory protein 5
  • Vertebrate Orthologs
    11
  • Human Ortholog
    REEP5, receptor accessory protein 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C5orf18, D5S346, DP1, TB2, Yip2e, YOP1
  • Links
    NCBI Gene ID: 7905
    neXtProt AC: NX_Q00765
    UniProt: Q00765

  • Chr Location
    5q22.2; chr5:112876384-112922334 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice homozygous for a gene trap insertion exhibit no detectable mutant phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000005873 Ensembl Gene Model | MGI Sequence Detail 28527 C57BL/6J ±  kb
transcript ENSMUST00000006027 Ensembl | MGI Sequence Detail 2894 Not Applicable  
polypeptide ENSMUSP00000006027 Ensembl | MGI Sequence Detail 189 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR004345 TB2/DP1/HVA22-related protein
Molecular
Reagents
less
  • All nucleic 190
    Genomic 2
    cDNA 187
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:2147209, MGI:2147316, MGI:2147366, MGI:2147419
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:28299 Kawai J, et al., Correspondence of RLGS-M spot behavior with tissue expression on mouse homologue of DP1/TB2 gene. Biochem Biophys Res Commun. 1995 Aug 24;213(3):967-74
  • Latest
    J:214135 Hashimoto Y, et al., Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia. J Biol Chem. 2014 May 9;289(19):12946-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory