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Fam3b
Gene Detail
Symbol

Name
ID
Fam3b
family with sequence similarity 3, member B
MGI:1270150
Synonyms
9030624C24Rik, D16Jhu19e, ORF9, Pander
Feature Type
protein coding gene
Genetic Map
Chromosome 16
57.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr16:97471050-97504936 bp, - strand
From VEGA annotation of GRCm38

  33887 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10766  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Fam3b

Human
homologs
Human Homolog FAM3B, family with sequence similarity 3, member B
NCBI Gene ID 54097
neXtProt AC  NX_P58499
Human Synonyms  2-21, C21orf11, C21orf76, ORF9, PANDER
Human Chr (Location)  21q22.3; chr21:41316734-41357727 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Genomic Mutations involving Fam3b (1)
Incidental mutations (data from APF )
 
Mice homozygous for a deletion of this gene display elevated blood glucose in glucose tolerance tests and elevated blood insulin after glucose injection, probably due to impaired insulin clearance.
 
Interactions
Fam3b interacts with 18 markers (Mir28b, Mir28c, Mir129-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process apoptotic process, insulin secretion
Component cell, extracellular region, ...
Function cytokine activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (67)    Tissues (66)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 49
RT-PCR 18
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(5) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000020067 (Evidence)
Ensembl Gene ModelENSMUSG00000022938 (Evidence)
Entrez Gene52793 (Evidence)
UniGene327932
DFCITC1585855
DoTSDT.97342007, DT.55137376
PDB2YOQ, 2YOP
Consensus CDS ProjectCCDS37416.1
International Mouse Knockout Project StatusFam3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020067 VEGA Gene Model | MGI Sequence Detail 33887 C57BL/6J ±  kb
transcript OTTMUST00000047735 VEGA | MGI Sequence Detail 853 Not Applicable 
polypeptide OTTMUSP00000021680 VEGA | MGI Sequence Detail 235 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(129 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026101 FAM3
Protein Ontology PR:000031851 protein FAM3B
References
(Earliest) J:50129 Cabin DE, et al., Physical and comparative mapping of distal mouse chromosome 16. 5 p5. Genome Res. 1998 Sep;8(9):940-50
(Latest) J:184528 Xiang JN, et al., Effect of PANDER in betaTC6-cell lipoapoptosis and the protective role of exendin-4. Biochem Biophys Res Commun. 2012 May 18;421(4):701-6
All references(37)
Other
accession IDs
MGI:1923006

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory