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Cyp2j5 Gene Detail
Summary
  • Symbol
    Cyp2j5
  • Name
    cytochrome P450, family 2, subfamily j, polypeptide 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270149
    NCBI Gene: 13109
  • Member of
    Cyp2j cluster
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:96517010-96552391 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 44.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    884 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270149
 protein coding gene Chr4:96517010-96552391 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028466
 protein coding gene Chr4:96728770-96762048 (-)
A/J MGP_AJ_G0028429
 protein coding gene Chr4:93324054-93358303 (-)
AKR/J MGP_AKRJ_G0028376
 protein coding gene Chr4:95617915-95651651 (-)
BALB/cJ MGP_BALBcJ_G0028447
 protein coding gene Chr4:93605399-93638832 (-)
C3H/HeJ MGP_C3HHeJ_G0028160
 protein coding gene Chr4:96414399-96451311 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028886
 protein coding gene Chr4:100418263-100457277 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026178
 protein coding gene Chr4:88829664-88862869 (-)
CAST/EiJ MGP_CASTEiJ_G0027600
 protein coding gene Chr4:94206696-94243147 (-)
CBA/J MGP_CBAJ_G0028129
 protein coding gene Chr4:103467200-103495497 (-)
DBA/2J MGP_DBA2J_G0028279
 protein coding gene Chr4:93129183-93159360 (-)
FVB/NJ MGP_FVBNJ_G0028246
 protein coding gene Chr4:91980457-92015287 (-)
LP/J MGP_LPJ_G0028379
 protein coding gene Chr4:97054393-97081644 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028274
 protein coding gene Chr4:109248783-109288780 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028924
 protein coding gene Chr4:95864830-95897190 (-)
PWK/PhJ MGP_PWKPhJ_G0027325
 protein coding gene Chr4:91242739-91278424 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027146
 protein coding gene Chr4:93295551-93326256 (-)
WSB/EiJ MGP_WSBEiJ_G0027678
 protein coding gene Chr4:95977869-96005755 (-)



Homology
more
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Synonyms
    CPJ2, CYPIIJ2
  • Links
    NCBI Gene ID: 1573
    UniProt: P51589

  • Chr Location
    1p32.1; chr1:59893308-59969212 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP2J2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female mice homozygous for a null mutation display increased systolic blood pressure, increased left ventricular weight, decreased litter sizes, decreased serum estrogen levels, and increased induced vasoconstriction responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    772
  • Tissues
    28
  • cDNA Data
    125
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13109 NCBI Gene Model | MGI Sequence Detail 35382 C57BL/6J ±  kb
    transcript NM_010007 RefSeq | MGI Sequence Detail 2345 ZRU/MplStud  
    polypeptide O54749 UniProt | EBI | MGI Sequence Detail 501 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 129
      cDNA 125
      Primer pair 3
      Other 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 11
    • Earliest
      J:47555 Ma J, et al., Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics. 1998 Apr 1;49(1):152-5
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory