About   Help   FAQ
Cyp2j5
Gene Detail
 Symbol
Name
ID
Cyp2j5
cytochrome P450, family 2, subfamily j, polypeptide 5
MGI:1270149
Feature Type protein coding gene
Genetic Map
Chromosome 4
44.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:96628773-96664154 bp, - strand
From VEGA annotation of GRCm38

  35382 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:122178  Vertebrate Homology Class
1 mouse

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2j5

Alleles
and
phenotypes
All alleles(1) : Targeted(1)
 
Female mice homozygous for a null mutation display increased systolic blood pressure, increased left ventricular weight, decreased litter sizes, decreased serum estrogen levels, and increased induced vasoconstriction responses.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (12)    Tissues (12)   
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RT-PCR 12
cDNA source data(123)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(125) cDNA(123) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000007943 (Evidence)
Ensembl Gene ModelENSMUSG00000052520 (Evidence)
Entrez Gene13109 (Evidence)
UniGene12838
DFCITC1575665, TC1653316
DoTSDT.532632
NIA Mouse Gene IndexU112954
EC1.14.14.1
Consensus CDS ProjectCCDS18371.1
International Mouse Knockout Project StatusCyp2j5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007943 VEGA Gene Model | MGI Sequence Detail 35382 C57BL/6J ±  kb
transcript OTTMUST00000018013 VEGA | MGI Sequence Detail 2345 Not Applicable 
polypeptide OTTMUSP00000008270 VEGA | MGI Sequence Detail 501 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(4) UniProt(3)
Polymorphisms PCR(1) : SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008071 Cytochrome P450, E-class, group I, CYP2J-like
Protein Ontology PR:000006239 cytochrome P450 2J5
References (Earliest) J:47555 Ma J, et al., Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics. 1998 Apr 1;49(1):152-5
(Latest) J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory