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Wipi1 Gene Detail
Summary
  • Symbol
    Wipi1
  • Name
    WD repeat domain, phosphoinositide interacting 1
  • Synonyms
    4930533H01Rik, D11Ertd498e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261864
    NCBI Gene: 52639
  • Gene Overview
    MyGene.info: WIPI1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:109573521-109611389 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 72.18 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261864
protein coding gene Chr11:109573331-109611967 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019336
protein coding gene Chr11:113140356-113184261 (-)
A/J MGP_AJ_G0019304
protein coding gene Chr11:108246127-108285046 (-)
AKR/J MGP_AKRJ_G0019273
protein coding gene Chr11:111496320-111541093 (-)
BALB/cJ MGP_BALBcJ_G0019278
protein coding gene Chr11:108676782-108716517 (-)
C3H/HeJ MGP_C3HHeJ_G0019087
protein coding gene Chr11:111797132-111837984 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019728
protein coding gene Chr11:116566551-116608345 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017351
protein coding gene Chr11:105469913-105508471 (-)
CAST/EiJ MGP_CASTEiJ_G0018640
protein coding gene Chr11:112931711-112973243 (-)
CBA/J MGP_CBAJ_G0019056
protein coding gene Chr11:121383877-121431251 (-)
DBA/2J MGP_DBA2J_G0019168
protein coding gene Chr11:107721027-107763583 (-)
FVB/NJ MGP_FVBNJ_G0019159
protein coding gene Chr11:107211795-107250884 (-)
LP/J MGP_LPJ_G0019238
protein coding gene Chr11:113551080-113596410 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019190
protein coding gene Chr11:120522467-120565956 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019765
protein coding gene Chr11:112059043-112101091 (-)
PWK/PhJ MGP_PWKPhJ_G0018405
protein coding gene Chr11:108890915-108930989 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018197
protein coding gene Chr11:111838492-111880772 (-)
WSB/EiJ MGP_WSBEiJ_G0018692
protein coding gene Chr11:111982672-112024909 (-)



Homology
more
  • Human Ortholog
    WIPI1, WD repeat domain, phosphoinositide interacting 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    WIPI1, WD repeat domain, phosphoinositide interacting 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATG18, ATG18A, WIPI49
  • Links
    NCBI Gene ID: 55062
    neXtProt AC: NX_Q5MNZ9
    UniProt: Q5MNZ9

  • Chr Location
    17q24.2; chr17:68421281-68457524 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 52639 NCBI Gene Model | MGI Sequence Detail 37869 C57BL/6J ±  kb
transcript NM_145940 RefSeq | MGI Sequence Detail 1817 C57BL/6  
polypeptide Q8R3E3 UniProt | EBI | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017425 WD repeat domain phosphoinositide-interacting protein 1
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR032909 WD repeat domain phosphoinositide-interacting protein 1
Molecular
Reagents
less
  • All nucleic 92
    cDNA 91
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1922049, MGI:2144526
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:233601 Akinduro O, et al., Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory