Wipi1
Gene Detail

Symbol Name ID

Wipi1 WD repeat domain, phosphoinositide interacting 1 MGI:1261864

Synonyms

4930533H01Rik, D11Ertd498e

Feature Type

protein coding gene

Genetic Map

Chromosome 11

72.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr11:109573331-109611967 bp, - strand From VEGA annotation of GRCm38   38637 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:117983  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Wipi1

Human homologs

Human Homolog		WIPI1, WD repeat domain, phosphoinositide interacting 1
NCBI Gene ID		55062
neXtProt AC		NX_Q5MNZ9
Human Synonyms		ATG18, ATG18A, WIPI49
Human Chr (Location)		17q24.2; chr17:66417422-66453653 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (25 annotations)

Process	autophagic vacuole assembly, autophagy, ...
Component	autophagic vacuole membrane, cytoplasm, ...
Function	androgen receptor binding, estrogen receptor binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (26)    Tissues (13)    Images (24)
Theiler Stages: 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	26

cDNA source data(89)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(92) cDNA(91) Primer pair(1)
Microarray probesets(10)

Other database links

VEGA Gene Model	OTTMUSG00000003347 (Evidence)
Ensembl Gene Model	ENSMUSG00000041895 (Evidence)
Entrez Gene	52639 (Evidence)
UniGene	35817
DFCI	TC1578346, TC1584398, TC1627936, TC1704188
NIA Mouse Gene Index	U033572
Consensus CDS Project	CCDS25582.1
International Mouse Knockout Project Status	Wipi1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003347	VEGA Gene Model | MGI Sequence Detail	38637	C57BL/6J
transcript	OTTMUST00000007035	VEGA | MGI Sequence Detail	2050	Not Applicable
polypeptide	OTTMUSP00000003347	VEGA | MGI Sequence Detail	446	Not Applicable

All sequences(51) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(37 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001680	WD40 repeat
InterPro	IPR017986	WD40-repeat-containing domain
InterPro	IPR015943	WD40/YVTN repeat-like-containing domain
Protein Ontology	PR:000017425	WD repeat domain phosphoinositide-interacting protein 1

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Other accession IDs

MGI:1922049, MGI:2144526