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Nit2 Gene Detail
Summary
  • Symbol
    Nit2
  • Name
    nitrilase family, member 2
  • Synonyms
    1190017B19Rik, D16Ertd502e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261838
    NCBI Gene: 52633
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:57156665-57167332 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 34.22 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261838
protein coding gene Chr16:57156665-57167341 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022895
protein coding gene Chr16:56306383-56318533 (-)
A/J MGP_AJ_G0022862
protein coding gene Chr16:53893663-53904299 (-)
AKR/J MGP_AKRJ_G0022834
protein coding gene Chr16:55596985-55607614 (-)
BALB/cJ MGP_BALBcJ_G0022862
protein coding gene Chr16:53996735-54007916 (-)
C3H/HeJ MGP_C3HHeJ_G0022625
protein coding gene Chr16:55786646-55797899 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023310
protein coding gene Chr16:57869573-57881817 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020821
protein coding gene Chr16:53545027-53555869 (-)
CAST/EiJ MGP_CASTEiJ_G0022152
protein coding gene Chr16:56173148-56183763 (-)
CBA/J MGP_CBAJ_G0022598
protein coding gene Chr16:60202902-60226718 (-)
DBA/2J MGP_DBA2J_G0022730
protein coding gene Chr16:53631062-53641686 (-)
FVB/NJ MGP_FVBNJ_G0022705
protein coding gene Chr16:53390683-53401296 (-)
LP/J MGP_LPJ_G0022797
protein coding gene Chr16:56119939-56141967 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022723
protein coding gene Chr16:60558035-60570101 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023325
protein coding gene Chr16:55741231-55751861 (-)
PWK/PhJ MGP_PWKPhJ_G0021891
protein coding gene Chr16:53941213-53952204 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021721
protein coding gene Chr16:55518983-55530374 (-)
WSB/EiJ MGP_WSBEiJ_G0022196
protein coding gene Chr16:55785298-55796751 (-)



Homology
more
  • Human Ortholog
    NIT2, nitrilase family member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NIT2, nitrilase family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HEL-S-8a
  • Links
    NCBI Gene ID: 56954
    neXtProt AC: NX_Q9NQR4
    UniProt: Q9NQR4

  • Chr Location
    3q12.2; chr3:100334718-100355634 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52633 NCBI Gene Model | MGI Sequence Detail 10668 C57BL/6J ±  kb
transcript NM_023175 RefSeq | MGI Sequence Detail 1292 Not Specified  
polypeptide Q9JHW2 UniProt | EBI | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 64
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913477
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory