Vps37a
Gene Detail

Symbol Name ID

Vps37a vacuolar protein sorting 37A (yeast) MGI:1261835

Synonyms

2210018P21Rik, 4930592A21Rik, D8Ertd531e

Feature Type

protein coding gene

Genetic Map

Chromosome 8

23.89 cM, cytoband B1.2
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr8:40511783-40551134 bp, + strand From NCBI annotation of GRCm38   39352 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:45120  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ESCRT-1 complex, Vps37A subunit, animal type
Gene Tree: Vps37a

Human homologs

Human Homolog		VPS37A, vacuolar protein sorting 37 homolog A (S. cerevisiae)
NCBI Gene ID		137492
neXtProt AC		NX_Q8NEZ2
Human Synonyms		HCRP1, PQBP2, SPG53
Human Chr (Location)		8p22; chr8:17104401-17155533 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human VPS37A

Alleles and phenotypes

All alleles(5) : Targeted(2) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	protein transport, transport, ...
Component	centrosome, cytoplasm, ...
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000031600 (Evidence)
Entrez Gene	52348 (Evidence)
NIA Mouse Gene Index	U042897
Consensus CDS Project	CCDS22254.1
International Mouse Knockout Project Status	Vps37a

Sequences

Length	Strain/Species
genomic	52348	NCBI Gene Model | MGI Sequence Detail	39352	C57BL/6J
transcript	NM_033560	RefSeq | MGI Sequence Detail	6379	C57BL/6
polypeptide	Q8CHS8	UniProt | EBI | MGI Sequence Detail	397	Not Applicable

All sequences(35) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(275 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009851	Modifier of rudimentary, Modr
InterPro	IPR016135	Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology	PR:000017335	vacuolar protein sorting-associated protein 37A

Graphical View of Protein Domain Structure

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:184769 Xue W, et al., A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8212-7
All references(32)

Other accession IDs

MGI:1914764, MGI:1923157, MGI:2142784