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Vps37a
Gene Detail
Symbol

Name
ID
Vps37a
vacuolar protein sorting 37A (yeast)
MGI:1261835
Synonyms
2210018P21Rik, 4930592A21Rik, D8Ertd531e
Feature Type
protein coding gene
Genetic Map
Chromosome 8
23.89 cM, cytoband B1.2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr8:40511783-40551134 bp, + strand
From NCBI annotation of GRCm38

  39352 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45120  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: VPS37A
Protein SuperFamily: ESCRT-1 complex, Vps37A subunit, animal type
Gene Tree: Vps37a

Human
homologs
VPS37A, vacuolar protein sorting 37 homolog A (S. cerevisiae)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 137492
neXtProt AC: NX_Q8NEZ2

Human Synonyms: HCRP1, PQBP2, SPG53

Human Chr (Location): 8p22; chr8:17246892-17298024 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human VPS37A

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Vps37a interacts with 421 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process protein transport, transport, ...
Component centrosome, cytoplasm, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(21)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase vps37a ; ZFIN vps37a    NEW 
Molecular
reagents
All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000031600 (Evidence)
Entrez Gene 52348 (Evidence)
NIA Mouse Gene Index U042897
Consensus CDS Project CCDS22254.1
International Mouse Phenotyping Consortium Status Vps37a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 52348 NCBI Gene Model | MGI Sequence Detail 39352 C57BL/6J ±  kb
transcript NM_033560 RefSeq | MGI Sequence Detail 6379 C57BL/6 
polypeptide Q8CHS8 UniProt | EBI | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(462 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009851 Modifier of rudimentary, Modr
InterPro IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology PR:000017335 vacuolar protein sorting-associated protein 37A
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:184769 Xue W, et al., A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8212-7
All references(31)
Other
accession IDs
MGI:1914764, MGI:1923157, MGI:2142784

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory