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Wnt2b
Gene Detail
Symbol

Name
ID
Wnt2b
wingless-type MMTV integration site family, member 2B
MGI:1261834
Synonyms
Wnt13
Feature Type
protein coding gene
Genetic Map
Chromosome 3
45.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:104944805-104961709 bp, - strand
From NCBI annotation of GRCm38

  16905 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22526  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: WNT2B
Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt2b

Human
homologs
WNT2B, wingless-type MMTV integration site family, member 2B
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7482
neXtProt AC: NX_Q93097

Human Synonyms: WNT13

Human Chr (Location): 1p13; chr1:112466541-112521288 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit no discernable phenotype.
 
Interactions
Wnt2b interacts with 246 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process canonical Wnt signaling pathway, cell-cell signaling, ...
Component extracellular region, extracellular space, ...
Function frizzled binding, protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (100 records)
Data Summary: Results (544)    Tissues (376)    Images (110)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 516
RT-PCR 26
RNase protection 2
cDNA source data(16)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA WNT2B ; Xenbase wnt2b ; ZFIN wnt2ba, wnt2bb    NEW 
Molecular
reagents
All nucleic(35) Genomic(1) cDNA(18) Primer pair(9) Other(7)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000027840 (Evidence)
Entrez Gene 22414 (Evidence)
UniGene 10740
DFCI TC1587834
DoTS DT.55110411
NIA Mouse Gene Index U024469
Consensus CDS Project CCDS17706.1
International Mouse Phenotyping Consortium Status Wnt2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 22414 NCBI Gene Model | MGI Sequence Detail 16905 C57BL/6J ±  kb
transcript NM_009520 RefSeq | MGI Sequence Detail 3573 C57BL/6 
polypeptide O70283 UniProt | EBI | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR009140 Wnt-2 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017441 protein Wnt-2b
Graphical View of Protein Domain Structure
References
(Earliest) J:47698 Zakin LD, et al., Structure and expression of Wnt13, a novel mouse Wnt2 related gene. Mech Dev. 1998 Apr;73(1):107-16
(Latest) J:221356 Snowball J, et al., Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall. Dev Biol. 2015 May 15;401(2):264-75
All references(134)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory