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Wnt2b
Gene Detail
 Symbol
Name
ID
Wnt2b
wingless related MMTV integration site 2b
MGI:1261834
Synonyms Wnt13
Feature Type protein coding gene
Genetic Map
Chromosome 3
45.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:104944805-104961709 bp, - strand
From NCBI annotation of GRCm38

  16905 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22526  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt2b

Human
homologs
Human Homolog WNT2B, wingless-type MMTV integration site family, member 2B
NCBI Gene ID 7482
neXtProt AC  NX_Q93097
Human Synonyms  WNT13, XWNT2
Human Chr (Location)  1p13; chr1:112467418-112521288 (+)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Mice homozygous for a knock-out allele exhibit no discernable phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process canonical Wnt signaling pathway, cell-cell signaling, ...
Component extracellular region, extracellular space, ...
Function frizzled binding, protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (93 records)
Data Summary: Results (550)    Tissues (377)    Images (110)
Theiler Stages: 1, 2, 3, 4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 516
RT-PCR 32
RNase protection 2
cDNA source data(16)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(35) Genomic(1) cDNA(18) Primer pair(9) Other(7)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000027840 (Evidence)
Entrez Gene22414 (Evidence)
UniGene10740
DFCITC1587834
DoTSDT.55110411
NIA Mouse Gene IndexU024469
Consensus CDS ProjectCCDS17706.1
International Mouse Knockout Project StatusWnt2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 22414 NCBI Gene Model | MGI Sequence Detail 16905 C57BL/6J ±  kb
transcript NM_009520 RefSeq | MGI Sequence Detail 3573 C57BL/6 
polypeptide O70283 UniProt | EBI | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR009140 Wnt-2 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017441 protein Wnt-2b
Graphical View of Protein Domain Structure
References (Earliest) J:47698 Zakin LD, et al., Structure and expression of Wnt13, a novel mouse Wnt2 related gene. Mech Dev. 1998 Apr;73(1):107-16
(Latest) J:202907 Grigoryan T, et al., Wnt/Rspondin/beta-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18174-9
All references(128)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory