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Wnt2b Gene Detail
Summary
  • Symbol
    Wnt2b
  • Name
    wingless-type MMTV integration site family, member 2B
  • Synonyms
    Wnt13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261834
    NCBI Gene: 22414
  • Gene Overview
    MyGene.info: WNT2B
Location & Maps
more
  • Sequence Map
    Chr3:104945272-104961921 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16650 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 45.88 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    WNT2B, Wnt family member 2B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WNT2B, Wnt family member 2B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    WNT13
  • Links
    NCBI Gene ID: 7482
    neXtProt AC: NX_Q93097

  • Chr Location
    1p13; chr1:112466541-112521288 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    12 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Wnt2b
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit no discernable phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000053152 VEGA Gene Model | MGI Sequence Detail 16650 C57BL/6J ±  kb
transcript OTTMUST00000132860 VEGA | MGI Sequence Detail 3318 Not Applicable  
polypeptide OTTMUSP00000070770 VEGA | MGI Sequence Detail 389 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    84 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    Genomic 1
    cDNA 18
    Primer pair 9
    Other 7

    Microarray probesets 3
References
more
  • Summaries
    All 138
    Developmental Gene Expression 106
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:47698 Zakin LD, et al., Structure and expression of Wnt13, a novel mouse Wnt2 related gene. Mech Dev. 1998 Apr;73(1):107-16
  • Latest
    J:229529 Gibbs BC, et al., Prickle1 mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects. Biol Open. 2016;5(3):323-35

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory