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Wnt2b Gene Detail
Summary
  • Symbol
    Wnt2b
  • Name
    wingless-type MMTV integration site family, member 2B
  • Synonyms
    Wnt13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261834
    NCBI Gene: 22414
  • Gene Overview
    MyGene.info: WNT2B
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:104945272-104961921 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 45.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261834
protein coding gene Chr3:104944805-104961921 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027714
protein coding gene Chr3:106284939-106301868 (-)
A/J MGP_AJ_G0027674
protein coding gene Chr3:102887229-102904201 (-)
AKR/J MGP_AKRJ_G0027639
protein coding gene Chr3:105427338-105443985 (-)
BALB/cJ MGP_BALBcJ_G0027686
protein coding gene Chr3:102675148-102691899 (-)
C3H/HeJ MGP_C3HHeJ_G0027416
protein coding gene Chr3:105800111-105817916 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028130
protein coding gene Chr3:110245775-110263131 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025470
protein coding gene Chr3:98996386-99013314 (-)
CAST/EiJ MGP_CASTEiJ_G0026872
protein coding gene Chr3:104915667-104933575 (-)
CBA/J MGP_CBAJ_G0027391
protein coding gene Chr3:114003068-114020014 (-)
DBA/2J MGP_DBA2J_G0027533
protein coding gene Chr3:102140219-102156868 (-)
FVB/NJ MGP_FVBNJ_G0027501
protein coding gene Chr3:100066026-100082929 (-)
LP/J MGP_LPJ_G0027640
protein coding gene Chr3:107691357-107708277 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027531
protein coding gene Chr3:120121279-120137933 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028185
protein coding gene Chr3:104978074-104994501 (-)
PWK/PhJ MGP_PWKPhJ_G0026598
protein coding gene Chr3:101919043-101935800 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026419
protein coding gene Chr3:103016488-103033217 (-)
WSB/EiJ MGP_WSBEiJ_G0026952
protein coding gene Chr3:105562632-105579642 (-)



Homology
more
  • Human Ortholog
    WNT2B, Wnt family member 2B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WNT2B, Wnt family member 2B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WNT13
  • Links
    NCBI Gene ID: 7482
    neXtProt AC: NX_Q93097
    UniProt: Q93097

  • Chr Location
    1p13.2; chr1:112466541-112521288 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit no discernable phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027840 Ensembl Gene Model | MGI Sequence Detail 16650 C57BL/6J ±  kb
    transcript ENSMUST00000029429 Ensembl | MGI Sequence Detail 3318 Not Applicable  
    polypeptide ENSMUSP00000029429 Ensembl | MGI Sequence Detail 389 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 41
      Genomic 1
      cDNA 20
      Primer pair 11
      Other 9

      Microarray probesets 3
    References
    more
    • Summaries
      All 161
      Developmental Gene Expression 122
      Diseases 1
      Gene Ontology 9
      Phenotypes 13
    • Earliest
      J:47698 Zakin LD, et al., Structure and expression of Wnt13, a novel mouse Wnt2 related gene. Mech Dev. 1998 Apr;73(1):107-16
    • Latest
      J:273296 Kaiser K, et al., WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nat Commun. 2019 Apr 2;10(1):1498

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/15/2019
    MGI 6.14
    The Jackson Laboratory