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Cand1 Gene Detail
Summary
  • Symbol
    Cand1
  • Name
    cullin associated and neddylation disassociated 1
  • Synonyms
    2310038O07Rik, 6330512O03Rik, D10Ertd516e, mKIAA0829
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261820
    NCBI Gene: 71902
  • Gene Overview
    MyGene.info: CAND1
Location & Maps
more
  • Sequence Map
    Chr10:119199255-119240055 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      40801 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 67.08 cM, cytoband D2
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CAND1, cullin associated and neddylation dissociated 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CAND1, cullin associated and neddylation dissociated 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TIP120, TIP120A
  • Links
    NCBI Gene ID: 55832
    neXtProt AC: NX_Q86VP6

  • Chr Location
    12q14; chr12:67269281-67314692 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Targeted
    2
  • Genomic Mutations
    1 involving Cand1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030921 VEGA Gene Model | MGI Sequence Detail 40801 C57BL/6J ±  kb
transcript OTTMUST00000076511 VEGA | MGI Sequence Detail 7766 Not Applicable  
polypeptide OTTMUSP00000040291 VEGA | MGI Sequence Detail 1230 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    172 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000005002 cullin-associated NEDD8-dissociated protein 1
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR013932 TATA-binding protein interacting (TIP20)
Molecular
Reagents
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  • All nucleic 224
    cDNA 223
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
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MGI:1919152, MGI:1923397, MGI:2143534, MGI:2143683
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:56734 Aoki T, et al., TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues. Biochem Biophys Res Commun. 1999 Aug 11;261(3):911-6
  • Latest
    J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory