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Rad51d
Gene Detail
Symbol

Name
ID
Rad51d
RAD51 homolog D
MGI:1261809
Synonyms
R51H3, Rad51l3
Feature Type
protein coding gene
Genetic Map
Chromosome 11
50.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr11:82876434-82890614 bp, - strand
From VEGA annotation of GRCm38

  14181 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2156  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: DNA repair and recombination protein, Rad51 type
Gene Tree: Rad51d

Human
homologs
Human Homolog RAD51D, RAD51 paralog D
NCBI Gene ID 5892
neXtProt AC  NX_O75771
Human Synonyms  BROVCA4, R51H3, RAD51L3, TRAD
Human Chr (Location)  17q11; chr17:35099792-35119869 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human RAD51D
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(11) Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for disruptions in this gene die as embryos before E11.5.
 
Phenotype Images(1)
Interactions
Rad51d interacts with 380 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process ATP catabolic process, cellular response to DNA damage stimulus, ...
Component centrosome, chromosome, ...
Function ATP binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (17)    Tissues (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 17
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(16) Primer pair(3)
Microarray probesets(7)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000932 VEGA Gene Model | MGI Sequence Detail 14181 C57BL/6J ±  kb
transcript OTTMUST00000001822 VEGA | MGI Sequence Detail 3426 Not Applicable 
polypeptide OTTMUSP00000000877 VEGA | MGI Sequence Detail 329 Not Applicable 

For the selected sequences
All sequences(118) RefSeq(16) UniProt(25)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(158 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR014774 Circadian clock protein KaiC/DNA repair protein RadA
InterPro IPR013632 DNA recombination and repair protein Rad51, C-terminal
InterPro IPR016467 DNA recombination and repair protein, RecA-like
InterPro IPR020588 DNA recombination/repair protein RecA/RadB, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000013677 DNA repair protein RAD51 homolog 4
References
(Earliest) J:47042 Cartwright R, et al., Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res. 1998 Apr 1;26(7):1653-9
(Latest) J:175085 Le Masson F, et al., Identification of Heat Shock Factor 1 Molecular and Cellular Targets during Embryonic and Adult Female Meiosis. Mol Cell Biol. 2011 Aug;31(16):3410-23
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory