Rad51d
Gene Detail

Symbol Name ID

Rad51d RAD51 homolog D MGI:1261809

Synonyms

R51H3, Rad51l3

Feature Type

protein coding gene

Genetic Map

Chromosome 11

50.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr11:82876434-82890614 bp, - strand From VEGA annotation of GRCm38   14181 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2156  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: DNA repair and recombination protein, Rad51 type
Gene Tree: Rad51d

Human homologs

Human Homolog		RAD51D, RAD51 homolog D (S. cerevisiae)
NCBI Gene ID		5892
neXtProt AC		NX_O75771
Human Synonyms		BROVCA4, R51H3, RAD51L3, TRAD
Human Chr (Location)		17q11; chr17:33426811-33446888 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RAD51D

Alleles and phenotypes

All alleles(14) : Targeted(3) Gene trapped(11)
 

Mice homozygous for disruptions in this gene die as embryos before E11.5.

 
Phenotype Images(1)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	DNA metabolic process, DNA recombination, ...
Component	nucleus
Function	ATP binding, DNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (17)    Tissues (12)   
Theiler Stages: 17, 22, 28

Assay Type	Results
RT-PCR	17

cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(16) Primer pair(3)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000000932 (Evidence)
Ensembl Gene Model	ENSMUSG00000018841 (Evidence)
Entrez Gene	19364 (Evidence)
DFCI	TC1579830, TC1594125, TC1595335, TC1595596, TC1596481, TC1596616, TC1599134, TC1602378, TC1617479
DoTS	DT.101355242, DT.101373766, DT.110543344, DT.482240, DT.488670, DT.91339421, DT.91339422, DT.91402292, DT.97367073
NIA Mouse Gene Index	U033179, U058096
Consensus CDS Project	CCDS36250.1
International Mouse Knockout Project Status	Rad51d

Sequences

Length	Strain/Species
genomic	OTTMUSG00000000932	VEGA Gene Model | MGI Sequence Detail	14181	C57BL/6J
transcript	OTTMUST00000001822	VEGA | MGI Sequence Detail	3426	Not Applicable
polypeptide	OTTMUSP00000000877	VEGA | MGI Sequence Detail	329	Not Applicable

All sequences(104) RefSeq(14) UniProt(13)

Polymorphisms

All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs(86 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003593	AAA+ ATPase domain
InterPro	IPR014774	Circadian clock protein KaiC/DNA repair protein RadA
InterPro	IPR013632	DNA recombination and repair protein Rad51, C-terminal
InterPro	IPR016467	DNA recombination and repair protein, RecA-like
InterPro	IPR020588	DNA recombination/repair protein RecA/RadB, ATP-binding domain
Protein Ontology	PR:000013677	DNA repair protein RAD51 4

References

(Earliest) J:47042 Cartwright R, et al., Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res. 1998 Apr 1;26(7):1653-9
(Latest) J:175085 Le Masson F, et al., Identification of Heat Shock Factor 1 Molecular and Cellular Targets during Embryonic and Adult Female Meiosis. Mol Cell Biol. 2011 Aug;31(16):3410-23
All references(40)