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Rad51d Gene Detail
Summary
  • Symbol
    Rad51d
  • Name
    RAD51 paralog D
  • Synonyms
    R51H3, Rad51l3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261809
    NCBI Gene: 19364
  • Gene Overview
    MyGene.info: RAD51D
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:82876434-82890614 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 50.30 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    156 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261809
protein coding gene Chr11:82871960-82890754 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018832
protein coding gene Chr11:84158391-84173490 (-)
A/J MGP_AJ_G0018799
protein coding gene Chr11:80925569-80939454 (-)
AKR/J MGP_AKRJ_G0018769
protein coding gene Chr11:83350935-83366208 (-)
BALB/cJ MGP_BALBcJ_G0018772
protein coding gene Chr11:81326782-81343372 (-)
C3H/HeJ MGP_C3HHeJ_G0018586
protein coding gene Chr11:83387057-83401259 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019224
protein coding gene Chr11:86678085-86695065 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016858
protein coding gene Chr11:77888399-77903272 (-)
CAST/EiJ MGP_CASTEiJ_G0018141
protein coding gene Chr11:83972822-83989573 (-)
CBA/J MGP_CBAJ_G0018557
protein coding gene Chr11:90431159-90450049 (-)
DBA/2J MGP_DBA2J_G0018665
protein coding gene Chr11:80499855-80514543 (-)
FVB/NJ MGP_FVBNJ_G0018654
protein coding gene Chr11:80025582-80039819 (-)
LP/J MGP_LPJ_G0018735
protein coding gene Chr11:84671965-84688513 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018681
protein coding gene Chr11:90631276-90647123 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019264
protein coding gene Chr11:83613425-83628772 (-)
PWK/PhJ MGP_PWKPhJ_G0017911
protein coding gene Chr11:81320430-81335799 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017702
protein coding gene Chr11:83237125-83251819 (-)
WSB/EiJ MGP_WSBEiJ_G0018193
protein coding gene Chr11:83500326-83514958 (-)



Homology
more
  • Human Ortholog
    RAD51D, RAD51 paralog D
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RAD51D, RAD51 paralog D
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BROVCA4, R51H3, RAD51L3, TRAD
  • Links
    NCBI Gene ID: 5892
    neXtProt AC: NX_O75771
    UniProt: O75771

  • Chr Location
    17q12; chr17:35099792-35119869 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human RAD51D associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    1 images
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene die as embryos before E11.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000018841 Ensembl Gene Model | MGI Sequence Detail 14181 C57BL/6J ±  kb
    transcript ENSMUST00000018985 Ensembl | MGI Sequence Detail 3426 Not Applicable  
    polypeptide ENSMUSP00000018985 Ensembl | MGI Sequence Detail 329 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      13 Sequences
    • InterPro Domains
      IPR003593 AAA+ ATPase domain
      IPR013632 DNA recombination and repair protein Rad51-like, C-terminal
      IPR016467 DNA recombination and repair protein, RecA-like
      IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
      IPR027417 P-loop containing nucleoside triphosphate hydrolase
      IPR033925 Rad51/DMC1/RadA
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 17
      Primer pair 3

      Microarray probesets 7
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 2
      Gene Ontology 9
      Phenotypes 16
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory