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Rad51d
Gene Detail
Symbol

Name
ID
Rad51d
RAD51 homolog D
MGI:1261809
Synonyms
R51H3, Rad51l3
Feature Type
protein coding gene
Genetic Map
Chromosome 11
50.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr11:82876434-82890614 bp, - strand
From VEGA annotation of GRCm38

  14181 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2156  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAD51D
Protein SuperFamily: DNA repair and recombination protein, Rad51 type
Gene Tree: Rad51d

Human
homologs
RAD51D, RAD51 paralog D
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5892
neXtProt AC: NX_O75771

Human Synonyms: BROVCA4, R51H3, RAD51L3, TRAD

Human Chr (Location): 17q11; chr17:35099792-35119869 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RAD51D

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(11) Targeted(4)
Genomic Mutations involving Rad51d (1)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for disruptions in this gene die as embryos before E11.5.
 
Phenotype Images(1)
Interactions
Rad51d interacts with 379 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process cellular response to DNA damage stimulus, chromosome organization, ...
Component centrosome, chromosome, ...
Function ATP binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (17)    Tissues (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 17
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rad51d ; ZFIN rad51d    NEW 
Molecular
reagents
All nucleic(19) cDNA(16) Primer pair(3)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000000932 (Evidence)
Ensembl Gene Model ENSMUSG00000018841 (Evidence)
Entrez Gene 19364 (Evidence)
DFCI TC1617479, TC1602378, TC1599134, TC1595596, TC1596616, TC1596481, TC1595335, TC1594125, TC1579830
DoTS DT.482240, DT.488670, DT.110543344, DT.101373766, DT.101355242, DT.91339422, DT.91339421, DT.97367073, DT.91402292
NIA Mouse Gene Index U033179, U058096
Consensus CDS Project CCDS36250.1, CCDS70267.1, CCDS70268.1
International Mouse Phenotyping Consortium Status Rad51d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000932 VEGA Gene Model | MGI Sequence Detail 14181 C57BL/6J ±  kb
transcript OTTMUST00000001822 VEGA | MGI Sequence Detail 3426 Not Applicable 
polypeptide OTTMUSP00000000877 VEGA | MGI Sequence Detail 329 Not Applicable 

For the selected sequences
All sequences(107) RefSeq(16) UniProt(13)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(158 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR014774 Circadian clock protein KaiC/DNA repair protein RadA
InterPro IPR013632 DNA recombination and repair protein Rad51, C-terminal
InterPro IPR016467 DNA recombination and repair protein, RecA-like
InterPro IPR020588 DNA recombination/repair protein RecA/RadB, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000013677 DNA repair protein RAD51 homolog 4
References
(Earliest) J:47042 Cartwright R, et al., Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res. 1998 Apr 1;26(7):1653-9
(Latest) J:175085 Le Masson F, et al., Identification of Heat Shock Factor 1 Molecular and Cellular Targets during Embryonic and Adult Female Meiosis. Mol Cell Biol. 2011 Aug;31(16):3410-23
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory