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Olr1
Gene Detail
 Symbol
Name
ID
Olr1
oxidized low density lipoprotein (lectin-like) receptor 1
MGI:1261434
Synonyms LOX-1, Scare1, SR-EI
Feature Type protein coding gene
Genetic Map
Chromosome 6
63.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:129485246-129507165 bp, - strand
From VEGA annotation of GRCm38

  21920 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1910  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Olr1

Human
homologs
Human Homolog OLR1, oxidized low density lipoprotein (lectin-like) receptor 1
NCBI Gene ID 4973
neXtProt AC  NX_P78380
Human Synonyms  CLEC8A, LOX1, LOXIN, SCARE1, SLOX1
Human Chr (Location)  12p13.2-p12.3; chr12:10158300-10172191 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human OLR1
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
 
Homozygous mutation of this gene results in no obvious phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell adhesion, cell death, ...
Component extracellular region, extrinsic component of plasma membrane, ...
Function carbohydrate binding, low-density lipoprotein receptor activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (48)    Tissues (15)   
Theiler Stages: 9, 11, 13, 15, 19, 22, 26, 28
Assay TypeResults
RNA in situ 7
RT-PCR 41
cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(17) Genomic(1) cDNA(11) Primer pair(3) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034583 (Evidence)
Ensembl Gene ModelENSMUSG00000030162 (Evidence)
Entrez Gene108078 (Evidence)
UniGene293626
DFCITC1633099, TC1663157, TC1678207
DoTSDT.101362207, DT.91283913, DT.99851250
NIA Mouse Gene IndexU027917
Consensus CDS ProjectCCDS20588.1
International Mouse Knockout Project StatusOlr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034583 VEGA Gene Model | MGI Sequence Detail 21920 C57BL/6J ±  kb
transcript OTTMUST00000087744 VEGA | MGI Sequence Detail 3570 Not Applicable 
polypeptide OTTMUSP00000047764 VEGA | MGI Sequence Detail 363 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(252 from dbSNP Build 137)    SNPs within 2kb including multiple locations(254)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000011634 oxidized low-density lipoprotein receptor 1
References (Earliest) J:47339 Hoshikawa H, et al., High affinity binding of oxidized LDL to mouse lectin-like oxidized LDL receptor (LOX-1). Biochem Biophys Res Commun. 1998 Apr 28;245(3):841-6
(Latest) J:198066 Dai Y, et al., Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-gamma. Biochem Biophys Res Commun. 2013 Feb 15;431(3):496-500
All references(49)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory