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Naga
Gene Detail
Symbol

Name
ID
Naga
N-acetyl galactosaminidase, alpha
MGI:1261422
Feature Type
protein coding gene
Genetic Map
Chromosome 15
38.56 cM, cytoband E
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:82329532-82338826 bp, - strand
From Ensembl annotation of GRCm38

  9295 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:221  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NAGA
Protein SuperFamily: glycosyl hydrolase, Mel1p type
Gene Tree: Naga

Human
homologs
NAGA, N-acetylgalactosaminidase, alpha-
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4668
neXtProt AC: NX_P17050

Human Synonyms: D22S674, GALB

Human Chr (Location): 22q11; chr22:42058334-42070871 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human NAGA

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Radiation induced(1) Targeted(1)
Genomic Mutations involving Naga (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Naga interacts with 97 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process carbohydrate catabolic process, carbohydrate metabolic process, ...
Component cytoplasm, extracellular exosome, ...
Function alpha-galactosidase activity, alpha-N-acetylgalactosaminidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (183)    Tissues (104)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 183
cDNA source data(81)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase naga    NEW 
Molecular
reagents
All nucleic(95) Genomic(13) cDNA(81) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000022453 (Evidence)
Entrez Gene 17939 (Evidence)
UniGene 20325
DFCI TC1732483, TC1578328
DoTS DT.94375896, DT.534786
NIA Mouse Gene Index U036449
EC 3.2.1.49
Consensus CDS Project CCDS27686.1
International Mouse Phenotyping Consortium Status Naga
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022453 Ensembl Gene Model | MGI Sequence Detail 9295 C57BL/6J ±  kb
transcript ENSMUST00000023088 Ensembl | MGI Sequence Detail 1913 Not Applicable 
polypeptide ENSMUSP00000023088 Ensembl | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(87 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013785 Aldolase-type TIM barrel
InterPro IPR000111 Glycoside hydrolase, clan GH-D
InterPro IPR002241 Glycoside hydrolase, family 27
InterPro IPR017853 Glycoside hydrolase, superfamily
InterPro IPR013780 Glycosyl hydrolase, family 13, all-beta
Protein Ontology PR:000010959 alpha-N-acetylgalactosaminidase
References
(Earliest) J:47737 Herrmann T, et al., Molecular cloning, structural organization, sequence, chromosomal assignment, and expression of the mouse alpha-N-acetylgalactosaminidase gene. Gene. 1998 May 12;211(2):205-14
(Latest) J:173543 Harper J, et al., The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory