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Pik3c2g
Gene Detail
Symbol

Name
ID
Pik3c2g
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
MGI:1203730
Feature Type
protein coding gene
Genetic Map
Chromosome 6
69.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:139587221-139969284 bp, + strand
From VEGA annotation of GRCm38

  382064 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3362  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: C2 phosphatidylinositol 3-kinase

Human
homologs
Human Homolog PIK3C2G, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
NCBI Gene ID 5288
neXtProt AC  NX_O75747
Human Synonyms  PI3K-C2-gamma, PI3K-C2GAMMA
Human Chr (Location)  12p12; chr12:18242978-18648418 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pik3c2g interacts with 240 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (107)    Tissues (105)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 107
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(3)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048882 VEGA Gene Model | MGI Sequence Detail 382064 C57BL/6J ±  kb
transcript OTTMUST00000124982 VEGA | MGI Sequence Detail 4407 Not Applicable 
polypeptide OTTMUSP00000067891 VEGA | MGI Sequence Detail 1021 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(4) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(5558 from dbSNP Build 137)    SNPs within 2kb including multiple locations(5560)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
InterPro IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
InterPro IPR002420 Phosphatidylinositol 3-kinase C2 (PI3K C2) domain
InterPro IPR000341 Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
InterPro IPR015433 Phosphatidylinositol Kinase
InterPro IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
InterPro IPR001683 Phox homologous domain
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000012717 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
References
(Earliest) J:46628 Misawa H, et al., Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain. Biochem Biophys Res Commun. 1998 Mar 17;244(2):531-9
(Latest) J:197548 Pihlajoki M, et al., Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice. Endocrinology. 2013 May;154(5):1754-67
All references(32)
Other
accession IDs
MGI:2141760

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory