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Pik3c2g
Gene Detail
 Symbol
Name
ID
Pik3c2g
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
MGI:1203730
Feature Type protein coding gene
Genetic Map
Chromosome 6
69.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:139587221-139969284 bp, + strand
From VEGA annotation of GRCm38

  382064 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3362  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: C2 phosphatidylinositol 3-kinase

Human
homologs
Human Homolog PIK3C2G, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
NCBI Gene ID 5288
neXtProt AC  NX_O75747
Human Synonyms  PI3K-C2-gamma, PI3K-C2GAMMA
Human Chr (Location)  12p12; chr12:18242978-18648418 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pik3c2g interacts with 240 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process chemotaxis, phosphatidylinositol-3-phosphate biosynthetic process, ...
Component Golgi apparatus, membrane, ...
Function 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (107)    Tissues (105)    Images (1)
Theiler Stages: 22, 24, 27, 28
Assay TypeResults
RNA in situ 107
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000048882 (Evidence)
Ensembl Gene ModelENSMUSG00000096062 (Evidence), ENSMUSG00000030228 (Evidence)
Entrez Gene18705 (Evidence)
DFCITC1588223, TC1592820, TC1596371, TC1597426, TC1614018, TC1615353, TC1645597
DoTSDT.101238396, DT.101308442, DT.101342830, DT.101707895, DT.101719628, DT.40136277, DT.40150377, DT.55159757, DT.91597707
NIA Mouse Gene IndexU007511
EC2.7.1.154
International Mouse Knockout Project StatusPik3c2g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048882 VEGA Gene Model | MGI Sequence Detail 382064 C57BL/6J ±  kb
transcript OTTMUST00000124982 VEGA | MGI Sequence Detail 4407 Not Applicable 
polypeptide OTTMUSP00000067891 VEGA | MGI Sequence Detail 1021 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(4) UniProt(7)
Polymorphisms RFLP(1) : SNPs within 2kb(5558 from dbSNP Build 137)    SNPs within 2kb including multiple locations(5560)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
InterPro IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
InterPro IPR002420 Phosphatidylinositol 3-kinase C2 (PI3K C2) domain
InterPro IPR000341 Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
InterPro IPR015433 Phosphatidylinositol Kinase
InterPro IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
InterPro IPR001683 Phox homologous domain
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000012717 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
References (Earliest) J:46628 Misawa H, et al., Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain. Biochem Biophys Res Commun. 1998 Mar 17;244(2):531-9
(Latest) J:197548 Pihlajoki M, et al., Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice. Endocrinology. 2013 May;154(5):1754-67
All references(32)
Other
accession IDs
MGI:2141760

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory