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Muc3 Gene Detail
Summary
  • Symbol
    Muc3
  • Name
    mucin 3, intestinal
  • Feature Type
    protein coding gene
  • IDs
    MGI:1203527
    NCBI Gene: 666339
  • Gene Overview
    MyGene.info: MUC17
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137134922-137149322 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    210 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1203527
protein coding gene Chr5:137134922-137166048 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030218
protein coding gene Chr5:141871760-141887454 (-)
A/J MGP_AJ_G0030186
protein coding gene Chr5:135708682-135723479 (-)
AKR/J MGP_AKRJ_G0030119
protein coding gene Chr5:140115912-140130283 (-)
BALB/cJ MGP_BALBcJ_G0030196
protein coding gene Chr5:137070169-137084514 (-)
C3H/HeJ MGP_C3HHeJ_G0029912
protein coding gene Chr5:140750276-140764643 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030648
protein coding gene Chr5:147128118-147142510 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0029322
protein coding gene Chr5:140155020-140170404 (-)
CBA/J MGP_CBAJ_G0029882
protein coding gene Chr5:152908217-152922592 (-)
DBA/2J MGP_DBA2J_G0030033
protein coding gene Chr5:135609537-135625508 (-)
FVB/NJ MGP_FVBNJ_G0029988
protein coding gene Chr5:134794797-134809482 (-)
LP/J MGP_LPJ_G0030122
protein coding gene Chr5:142302789-142317374 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030020
protein coding gene Chr5:155782349-155796752 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030689
protein coding gene Chr5:139941081-139955306 (-)
PWK/PhJ MGP_PWKPhJ_G0029035
protein coding gene Chr5:134696998-134712386 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028871
protein coding gene Chr5:137531399-137546064 (-)
WSB/EiJ MGP_WSBEiJ_G0029395
protein coding gene Chr5:140683472-140697827 (-)



Homology
more
  • Human Ortholog
    MUC17, mucin 17, cell surface associated
  • Vertebrate Orthologs
    2
  • Human Ortholog
    MUC17, mucin 17, cell surface associated
    Orthology source: HGNC
  • Synonyms
    MUC-17, MUC3, MUC-3
  • Links
    NCBI Gene ID: 140453
    neXtProt AC: NX_Q685J3
    UniProt: Q685J3

  • Chr Location
    7q22.1; chr7:101020083-101058859 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037390 Ensembl Gene Model | MGI Sequence Detail 14401 C57BL/6J ±  kb
transcript ENSMUST00000041226 Ensembl | MGI Sequence Detail 1853 Not Applicable  
polypeptide ENSMUSP00000045196 Ensembl | MGI Sequence Detail 378 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 3
  • Earliest
    J:46806 Shekels LL, et al., Cloning and characterization of mouse intestinal MUC3 mucin: 3' sequence contains epidermal-growth-factor-like domains. Biochem J. 1998 Mar 15;330(Pt 3):1301-8
  • Latest
    J:205075 Pelaseyed T, et al., Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes. Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C457-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory