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Rrp1 Gene Detail
Summary
  • Symbol
    Rrp1
  • Name
    ribosomal RNA processing 1 homolog (S. cerevisiae)
  • Synonyms
    Nnp1, NNP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1203500
    NCBI Gene: 18114
  • Gene Overview
    MyGene.info: RRP1
Location & Maps
more
  • Sequence Map
    Chr10:78400362-78413043 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12682 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    RRP1, ribosomal RNA processing 1
  • Human Ortholog
    RRP1, ribosomal RNA processing 1
    Orthology source: HGNC
  • Synonyms
    D21S2056E, NNP-1, NOP52, RRP1A
  • Links
    NCBI Gene ID: 8568
    neXtProt AC: NX_P56182

  • Chr Location
    21q22.3; chr21:43789535-43804102 (+)  GRCh38.p2

  • HCOP
    human homology predictions: RRP1
  • Gene Tree
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Rrp1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18114 NCBI Gene Model | MGI Sequence Detail 12682 C57BL/6J ±  kb
transcript NM_010925 RefSeq | MGI Sequence Detail 2008 C57BL/6  
polypeptide P56183 UniProt | EBI | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    51 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014309 ribosomal RNA processing protein 1 homolog A
  • InterPro Domains
    IPR010301 Nucleolar, Nop52
Molecular
Reagents
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  • All nucleic 223
    Genomic 9
    cDNA 213
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
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MGI:2143715, MGI:2143716, MGI:2143730
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Diseases 2
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:41225 Jansen E, et al., The NNP-1 gene (D21S2056E), which encodes a novel nuclear protein, maps in close proximity to the cystatin B gene within the EPM1 and APECED critical region on 21q22.3. Genomics. 1997 Jun 1;42(2):336-41
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory