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Zfml
Gene Detail
 Symbol
Name
ID
Zfml
zinc finger, matrin-like
MGI:1203484
Synonyms mNP220, Np220
Feature Type protein coding gene
Genetic Map
Chromosome 6
36.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:83914353-83986869 bp, + strand
From Ensembl annotation of GRCm38

  72517 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7447  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Zfml

Human
homologs
Human Homolog ZNF638, zinc finger protein 638
NCBI Gene ID 27332
neXtProt AC  NX_Q14966
Human Synonyms  NP220, ZFML, Zfp638
Human Chr (Location)  2p13.1; chr2:71276593-71435061 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Gene trapped(29)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Zfml interacts with 148 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component intracellular membrane-bounded organelle, nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (59)    Tissues (53)    Images (7)
Theiler Stages: 2, 3, 4, 5, 16, 17, 21, 23, 28
Assay TypeResults
RNA in situ 49
RT-PCR 10
cDNA source data(166)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(168) cDNA(166) Primer pair(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000030016 (Evidence)
Entrez Gene18139 (Evidence)
UniGene132392
DFCITC1575616, TC1584475, TC1593111, TC1594167, TC1606730
DoTSDT.101222715, DT.101381386, DT.101722299, DT.101736616, DT.103585254, DT.482404, DT.491653
NIA Mouse Gene IndexU007090
Consensus CDS ProjectCCDS20288.1, CCDS51823.1
International Mouse Knockout Project StatusZfml
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030016 Ensembl Gene Model | MGI Sequence Detail 72517 C57BL/6J ±  kb
transcript ENSMUST00000032088 Ensembl | MGI Sequence Detail 6366 Not Applicable 
polypeptide ENSMUSP00000032088 Ensembl | MGI Sequence Detail 1926 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(26) UniProt(9)
Polymorphisms SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR000690 Zinc finger, C2H2-type matrin
InterPro IPR022755 Zinc finger, double-stranded RNA binding
InterPro IPR003604 Zinc finger, U1-type
Protein Ontology PR:000018045 zinc finger protein 638
References (Earliest) J:33575 Matsushima Y, et al., A family of novel DNA-binding nuclear proteins having polypyrimidine tract-binding motif and arginine/serine-rich motif. Biochem Biophys Res Commun. 1996 Jun 14;223(2):427-33
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2141390

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory