Rhd
Gene Detail

Symbol Name ID

Rhd Rh blood group, D antigen MGI:1202882

Synonyms

Rh, Rhced, Rhl1

Feature Type

protein coding gene

Genetic Map

Chromosome 4

67.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr4:134864536-134896172 bp, + strand From VEGA annotation of GRCm38   31637 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7918  Vertebrate Homology Class
2 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: erythrocyte membrane protein RhD
Gene Tree: Rhd

Human homologs

Human Homolog		RHCE, Rh blood group, CcEe antigens
NCBI Gene ID		6006
neXtProt AC		NX_P18577
Human Synonyms		CD240CE, RH, RH30A, Rh4, RHC, RHE, RhIVb(J), RHIXB, RHPI, RhVI, RhVIII
Human Chr (Location)		1p36.11; chr1:25688740-25747363 (-)  GRCh37.p10
Human Homolog		RHD, Rh blood group, D antigen
NCBI Gene ID		6007
neXtProt AC		NX_Q02161
Human Synonyms		CD240D, DIIIc, RH, RH30, Rh4, RHCED, RhDCw, RHDel, RHDVA(TT), RhII, RhK562-II, RhPI, RHPII, RHXIII
Human Chr (Location)		1p36.11; chr1:25598981-25656936 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(20) : Targeted(4) Gene trapped(16)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	ammonium transmembrane transport, ammonium transport, ...
Component	integral to membrane, membrane
Function	ammonium transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (139)    Tissues (114)    Images (20)
Theiler Stages: 1, 2, 3, 5, 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	113
Northern blot	12
RT-PCR	14

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(29) Genomic(2) cDNA(24) Primer pair(1) Other(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000011094 (Evidence)
Ensembl Gene Model	ENSMUSG00000028825 (Evidence)
Entrez Gene	19746 (Evidence)
UniGene	195461
DFCI	TC1576143
DoTS	DT.110836110, DT.487679
NIA Mouse Gene Index	U004941
Consensus CDS Project	CCDS18778.1
International Mouse Knockout Project Status	Rhd

Sequences

Length	Strain/Species
genomic	OTTMUSG00000011094	VEGA Gene Model | MGI Sequence Detail	31637	C57BL/6J
transcript	OTTMUST00000025966	VEGA | MGI Sequence Detail	1514	Not Applicable
polypeptide	OTTMUSP00000011894	VEGA | MGI Sequence Detail	418	Not Applicable

All sequences(35) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(1) : SNPs(231 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR024041	Ammonium transporter AmtB-like
InterPro	IPR002229	Blood group Rhesus C/E/D polypeptide
Protein Ontology	PR:000001442	blood group RhD polypeptide

References

(Earliest) J:49131 Kitano T, et al., Conserved evolution of the Rh50 gene compared to its homologous Rh blood group gene. Biochem Biophys Res Commun. 1998 Aug 10;249(1):78-85
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)

Other accession IDs

MGI:1888985