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Cuzd1
Gene Detail
Symbol

Name
ID
Cuzd1
CUB and zona pellucida-like domains 1
MGI:1202881
Synonyms
ERG-1, Itmap1, UO-44, UTCZP
Feature Type
protein coding gene
Genetic Map
Chromosome 7
73.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:131308554-131322292 bp, - strand
From VEGA annotation of GRCm38

  13739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7389  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 2 western clawed frog; 3 zebrafish

HCOP human homology predictions: CUZD1
Gene Tree: Cuzd1

Human
homologs
CUZD1, CUB and zona pellucida-like domains 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 50624
neXtProt AC: NX_Q86UP6

Human Synonyms: ERG-1, UO-44

Human Chr (Location): 10q26.13; chr10:122832155-122846175 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for disruption of this gene have a normal phenotype. However, they show an increased sesceptibility to induced pancreatitis.
 
Interactions
Cuzd1 interacts with 36 markers (Mir29b-1, Mir30a, Mir30d, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell adhesion, cell cycle, ...
Component cytoplasmic vesicle, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100485179, LOC100495929    NEW 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000045956 (Evidence)
Ensembl Gene Model ENSMUSG00000040205 (Evidence)
Entrez Gene 16433 (Evidence)
UniGene 142717
DFCI TC1582386
DoTS DT.60118748
Consensus CDS Project CCDS40157.1
International Mouse Phenotyping Consortium Status Cuzd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045956 VEGA Gene Model | MGI Sequence Detail 13739 C57BL/6J ±  kb
transcript OTTMUST00000120072 VEGA | MGI Sequence Detail 2256 Not Applicable 
polypeptide OTTMUSP00000066609 VEGA | MGI Sequence Detail 607 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(163 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000859 CUB domain
InterPro IPR001507 Zona pellucida domain
Protein Ontology PR:000006057 CUB and zona pellucida-like domain-containing protein 1
References
(Earliest) J:46397 Kasik JW, A cDNA cloned from pregnant mouse uterus exhibits temporo-spatial expression and predicts a novel protein. Biochem J. 1998 Mar 1;330(Pt 2):947-50
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory