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Meig1
Gene Detail
 Symbol
Name
ID
Meig1
meiosis expressed gene 1
MGI:1202878
Synonyms Meg1
Feature Type protein coding gene
Genetic Map
Chromosome 2
1.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:3409043-3422648 bp, - strand
From VEGA annotation of GRCm38

  13606 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56414  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Meig1

Human
homologs
Human Homolog MEIG1, meiosis/spermiogenesis associated 1
NCBI Gene ID 644890
neXtProt AC  NX_Q5JSS6
Human Synonyms  bA2K17.3, SPATA39
Human Chr (Location)  10p13; chr10:14954383-14972857 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit male sterility with arrested spermatogenesis, absent sperm flagellum, and deformed sperm heads.
 
Phenotype Images(2)
Interactions
Meig1 interacts with 41 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process cell differentiation, meiotic nuclear division, ...
Component nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (2)    Tissues (1)    Images (1)
Theiler Stages: 28
Assay TypeResults
RT-PCR 2
cDNA source data(147)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(148) cDNA(147) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000010782 (Evidence)
Ensembl Gene ModelENSMUSG00000026650 (Evidence)
Entrez Gene104362 (Evidence)
UniGene2688
DFCITC1574905, TC1590032
DoTSDT.103566267, DT.486328
NIA Mouse Gene IndexU022237
Consensus CDS ProjectCCDS38038.1
International Mouse Knockout Project StatusMeig1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010782 VEGA Gene Model | MGI Sequence Detail 13606 C57BL/6J ±  kb
transcript OTTMUST00000025215 VEGA | MGI Sequence Detail 603 Not Applicable 
polypeptide OTTMUSP00000011564 VEGA | MGI Sequence Detail 88 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020186 Meiosis-expressed gene 1 protein
Protein Ontology PR:000010315 meiosis expressed gene 1 protein
References (Earliest) J:2557 Don J, et al., Identification and characterization of the regulated pattern of expression of a novel mouse gene, meg1, during the meiotic cell cycle. Cell Growth Differ. 1992 Aug;3(8):495-505
(Latest) J:194944 Teves ME, et al., Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice. Andrology. 2013 Jan;1(1):37-46
All references(38)
Other
accession IDs
MGD-MRK-12188, MGI:96959

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory