Dgcr6
Gene Detail

Symbol

Name
ID

Dgcr6
DiGeorge syndrome critical region gene 6
MGI:1202877

Feature Type

protein coding gene

Genetic Map

Chromosome 16
11.19 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(10)

Sequence Map

Chr16:18052860-18071632 bp, + strand From VEGA annotation of GRCm38   18773 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:4152  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Gene Tree: Dgcr6

Mutations,
alleles, and
phenotypes

All mutations/alleles(12) : Targeted(12)
Genomic Mutations involving Dgcr6 (9)
Mutations Annotated to Human Diseases (3)   

Interactions

Dgcr6 interacts with 59 markers (Mir1a-1, Mir1a-2, Mir16-2, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (3 annotations)

Process	biological_process
Component	cellular_component
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (4 records)

Data Summary: Results (80)    Tissues (60)    Images (12)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	36
Northern blot	12
RT-PCR	32

cDNA source data(50)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas

Molecular
reagents

All nucleic(80) Genomic(29) cDNA(50) Primer pair(1)
Microarray probesets(6)

Other database
links

VEGA Gene Model	OTTMUSG00000028179 (Evidence)
Ensembl Gene Model	ENSMUSG00000003531 (Evidence)
Entrez Gene	13353 (Evidence)
UniGene	27155
DFCI	TC1658596, TC1647482, TC1638998, TC1580739
Consensus CDS Project	CCDS28016.1
International Mouse Knockout Project Status	Dgcr6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028179	VEGA Gene Model | MGI Sequence Detail	18773	C57BL/6J
transcript	OTTMUST00000069810	VEGA | MGI Sequence Detail	1415	Not Applicable
polypeptide	OTTMUSP00000035508	VEGA | MGI Sequence Detail	233	Not Applicable

All sequences(78) RefSeq(15) UniProt(6)

Polymorphisms

SNPs within 2kb(48 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR010849	DiGeorge syndrome critical 6
Protein Ontology	PR:000006439	protein DGCR6

References

(Earliest) J:44451 Botta A, et al., Comparative mapping of the DiGeorge syndrome region in mouse shows inconsistent gene order and differential degree of gene conservation. Mamm Genome. 1997 Dec;8(12):890-5
(Latest) J:213451 Karpinski BA, et al., Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Dis Model Mech. 2014 Feb;7(2):245-57
All references(37)

Other
accession IDs

MGI:2146581