About   Help   FAQ
Dgcr6 Gene Detail
Summary
  • Symbol
    Dgcr6
  • Name
    DiGeorge syndrome critical region gene 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202877
    NCBI Gene: 13353
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17870724-17889496 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.19 cM, cytoband B2
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202877
protein coding gene Chr16:17870724-17889497 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022600
protein coding gene Chr16:15245999-15267464 (+)
A/J MGP_AJ_G0022561
protein coding gene Chr16:14493214-14511885 (+)
AKR/J MGP_AKRJ_G0022538
protein coding gene Chr16:15058937-15077948 (+)
BALB/cJ MGP_BALBcJ_G0022566
protein coding gene Chr16:14642124-14661763 (+)
C3H/HeJ MGP_C3HHeJ_G0022333
protein coding gene Chr16:15224186-15248234 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023015
protein coding gene Chr16:15507879-15532776 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020535
protein coding gene Chr16:14549045-14567788 (+)
CAST/EiJ MGP_CASTEiJ_G0021860
protein coding gene Chr16:15112491-15130997 (+)
CBA/J MGP_CBAJ_G0022302
protein coding gene Chr16:16183604-16203447 (+)
DBA/2J MGP_DBA2J_G0022434
protein coding gene Chr16:14403737-14424607 (+)
FVB/NJ MGP_FVBNJ_G0022409
protein coding gene Chr16:14450285-14469005 (+)
LP/J MGP_LPJ_G0022501
protein coding gene Chr16:15035906-15056305 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022431
protein coding gene Chr16:15855938-15879610 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023026
protein coding gene Chr16:14994239-15012981 (+)
PWK/PhJ MGP_PWKPhJ_G0021602
protein coding gene Chr16:14669414-14688662 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021430
protein coding gene Chr16:14959243-14977839 (+)
WSB/EiJ MGP_WSBEiJ_G0021906
protein coding gene Chr16:14979501-15000410 (+)



Homology
more
  • Human Ortholog
    DGCR6, DiGeorge syndrome critical region gene 6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DGCR6, DiGeorge syndrome critical region gene 6
  • Links
    NCBI Gene ID: 8214
    neXtProt AC: NX_Q14129
    UniProt: Q14129

  • Chr Location
    22q11.21; chr22:18906223-18912088 (+)  GRCh38.p7

  • Human Ortholog
    DGCR6L, DiGeorge syndrome critical region gene 6 like
  • Synonyms
    DGCR6
  • Links
    NCBI Gene ID: 85359
    neXtProt AC: NX_Q9BY27
    UniProt: Q9BY27

  • Chr Location
    chr22:20314238-20320105 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human DGCR6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    81 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003531 Ensembl Gene Model | MGI Sequence Detail 18773 C57BL/6J ±  kb
transcript ENSMUST00000155387 Ensembl | MGI Sequence Detail 1415 Not Applicable  
polypeptide ENSMUSP00000123053 Ensembl | MGI Sequence Detail 233 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    Genomic 29
    cDNA 51
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2146581
References
more
  • Summaries
    All 112
    Developmental Gene Expression 5
    Diseases 6
    Phenotypes 81
  • Earliest
    J:44451 Botta A, et al., Comparative mapping of the DiGeorge syndrome region in mouse shows inconsistent gene order and differential degree of gene conservation. Mamm Genome. 1997 Dec;8(12):890-5
  • Latest
    J:306108 Karpinski BA, et al., Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome. Dis Model Mech. 2022 Feb 1;15(2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/12/2021
MGI 6.17
The Jackson Laboratory