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Art4 Gene Detail
Summary
  • Symbol
    Art4
  • Name
    ADP-ribosyltransferase 4
  • Synonyms
    4432404K01Rik, DO, DOK1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202710
    NCBI Gene: 109978
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136825449-136834598 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.72 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    520 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202710
 protein coding gene Chr6:136825449-136834731 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031428
 protein coding gene Chr6:141330904-141362621 (-)
A/J MGP_AJ_G0031404
 protein coding gene Chr6:135740958-135750778 (-)
AKR/J MGP_AKRJ_G0031332
 protein coding gene Chr6:139873932-139883446 (-)
BALB/cJ MGP_BALBcJ_G0031411
 protein coding gene Chr6:135607226-135623039 (-)
C3H/HeJ MGP_C3HHeJ_G0031133
 protein coding gene Chr6:139902713-139912229 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031873
 protein coding gene Chr6:145190059-145199056 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029002
 protein coding gene Chr6:134856425-134865342 (-)
CAST/EiJ MGP_CASTEiJ_G0030501
 protein coding gene Chr6:139402360-139414006 (-)
CBA/J MGP_CBAJ_G0031093
 protein coding gene Chr6:150627339-150637328 (-)
DBA/2J MGP_DBA2J_G0031250
 protein coding gene Chr6:134616770-134626031 (-)
FVB/NJ MGP_FVBNJ_G0031201
 protein coding gene Chr6:133517148-133525718 (-)
LP/J MGP_LPJ_G0031334
 protein coding gene Chr6:141453839-141469000 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031241
 protein coding gene Chr6:154511392-154522098 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031905
 protein coding gene Chr6:139616954-139626719 (-)
PWK/PhJ MGP_PWKPhJ_G0030228
 protein coding gene Chr6:133112472-133125134 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030052
 protein coding gene Chr6:137880659-137891460 (-)
WSB/EiJ MGP_WSBEiJ_G0030594
 protein coding gene Chr6:140251140-140267139 (-)



Homology
more
  • Human Ortholog
    ART4, ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ART4, ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
  • Synonyms
    ARTC4, CD297, DO, DO/ART4, DOK1
  • Links
    NCBI Gene ID: 420
    UniProt: Q93070

  • Chr Location
    12p12.3; chr12:14825569-14843526 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    845
  • Tissues
    102
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 109978 NCBI Gene Model | MGI Sequence Detail 9150 C57BL/6J ±  kb
transcript NM_026639 RefSeq | MGI Sequence Detail 2384 ZRU/MplStud  
polypeptide Q9CRA0 UniProt | EBI | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    Genomic 1
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915507
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory