About   Help   FAQ
Chrna9
Gene Detail
Symbol

Name
ID
Chrna9
cholinergic receptor, nicotinic, alpha polypeptide 9
MGI:1202403
Synonyms
2410015I05Rik, Acra9, Gm8311
Feature Type
protein coding gene
Genetic Map
Chromosome 5
33.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:65934921-65977326 bp, + strand
From VEGA annotation of GRCm38

  42406 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Chrna9
Mutations,
alleles, and
phenotypes
All mutations/alleles(38) : Gene trapped(32) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in abnormal innervation of the outer hair cells and depressed olivocochlear response.
 
Interactions
Chrna9 interacts with 17 markers (Mir24-1, Mir24-2, Mir182, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cation transmembrane transport, cation transport, ...
Component cell, cytosol
Function acetylcholine-activated cation-selective channel activity, protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(7)
External Resources: Allen Institute   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000022200 (Evidence)
Ensembl Gene ModelENSMUSG00000029205 (Evidence)
Entrez Gene102635442, 231252
UniGene486671
DFCITC1605754
DoTSDT.87059044
NIA Mouse Gene IndexU273768, U005638
Consensus CDS ProjectCCDS39101.1
International Mouse Knockout Project StatusChrna9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022200 VEGA Gene Model | MGI Sequence Detail 42406 C57BL/6J ±  kb
transcript OTTMUST00000052746 VEGA | MGI Sequence Detail 1843 Not Applicable 
polypeptide OTTMUSP00000025052 VEGA | MGI Sequence Detail 479 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(8)
Polymorphisms
SNPs within 2kb(137 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
InterPro IPR027361 Nicotinic acetylcholine-gated receptor, transmembrane domain
InterPro IPR002394 Nicotinic acetylcholine receptor
Protein Ontology PR:000005461 neuronal acetylcholine receptor subunit alpha-9
References
(Earliest) J:30598 Glowatzki E, et al., Cell-specific expression of the alpha 9 n-ACh receptor subunit in auditory hair cells revealed by single-cell RT-PCR. Proc R Soc Lond B Biol Sci. 1995 Nov 22;262(1364):141-7
(Latest) J:214304 Clause A, et al., The precise temporal pattern of prehearing spontaneous activity is necessary for tonotopic map refinement. Neuron. 2014 May 21;82(4):822-35
All references(51)
Other
accession IDs
MGI:1917242, MGI:3643549

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory