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Gpr27 Gene Detail
Summary
  • Symbol
    Gpr27
  • Name
    G protein-coupled receptor 27
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202299
    NCBI Gene: 14761
  • Gene Overview
    MyGene.info: GPR27
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:99692679-99693818 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 46.22 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202299
protein coding gene Chr6:99692679-99695066 (.)
129S1/SvImJ MGP_129S1SvImJ_G0031083
protein coding gene Chr6:101656831-101659218 (+)
A/J MGP_AJ_G0031052
protein coding gene Chr6:97780523-97782910 (+)
AKR/J MGP_AKRJ_G0030983
protein coding gene Chr6:100454266-100456653 (+)
BALB/cJ MGP_BALBcJ_G0031063
protein coding gene Chr6:97748909-97751296 (+)
C3H/HeJ MGP_C3HHeJ_G0030645
protein coding gene Chr6:83944611-83946998 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031522
protein coding gene Chr6:104221006-104223393 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028686
protein coding gene Chr6:95610541-95612920 (+)
CAST/EiJ MGP_CASTEiJ_G0030170
protein coding gene Chr6:100693488-100695876 (+)
CBA/J MGP_CBAJ_G0030749
protein coding gene Chr6:108215926-108218313 (+)
DBA/2J MGP_DBA2J_G0030902
protein coding gene Chr6:96918124-96920511 (+)
FVB/NJ MGP_FVBNJ_G0030856
protein coding gene Chr6:96088070-96090457 (+)
LP/J MGP_LPJ_G0030982
protein coding gene Chr6:101701095-101703482 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030890
protein coding gene Chr6:112010370-112012757 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031549
protein coding gene Chr6:100376764-100379151 (+)
PWK/PhJ MGP_PWKPhJ_G0029886
protein coding gene Chr6:95927929-95930304 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029714
protein coding gene Chr6:99268113-99270500 (+)
WSB/EiJ MGP_WSBEiJ_G0030254
protein coding gene Chr6:100872417-100874804 (+)



Homology
more
  • Human Ortholog
    GPR27, G protein-coupled receptor 27
  • Vertebrate Orthologs
    5
  • Human Ortholog
    GPR27, G protein-coupled receptor 27
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SREB1
  • Links
    NCBI Gene ID: 2850
    neXtProt AC: NX_Q9NS67
    UniProt: Q9NS67

  • Chr Location
    3p13; chr3:71754050-71755177 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14761 NCBI Gene Model | MGI Sequence Detail 1140 C57BL/6J ±  kb
transcript NM_008158 RefSeq | MGI Sequence Detail 2712 C57BL/6  
polypeptide O54897 UniProt | EBI | MGI Sequence Detail 379 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:45954 O'Dowd BF, et al., Discovery of three novel G-protein-coupled receptor genes. Genomics. 1998 Jan 15;47(2):310-3
  • Latest
    J:181489 Ku GM, et al., An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production. PLoS Genet. 2012 Jan;8(1):e1002449

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory