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Gpr27 Gene Detail
Summary
  • Symbol
    Gpr27
  • Name
    G protein-coupled receptor 27
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202299
    NCBI Gene: 14761
  • Gene Overview
    MyGene.info: GPR27
Location & Maps
more
  • Sequence Map
    Chr6:99692679-99695066 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2388 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 46.22 cM, cytoband E1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GPR27, G protein-coupled receptor 27
  • Vertebrate Orthologs
    5
  • Human Ortholog
    GPR27, G protein-coupled receptor 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SREB1
  • Links
    NCBI Gene ID: 2850
    neXtProt AC: NX_Q9NS67

  • Chr Location
    3p21-p14; chr3:71754050-71755177 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    1
  • Spontaneous
    1
  • Genomic Mutations
    1 involving Gpr27
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057659 VEGA Gene Model | MGI Sequence Detail 2388 C57BL/6J ±  kb
transcript OTTMUST00000141687 VEGA | MGI Sequence Detail 2388 Not Applicable  
polypeptide OTTMUSP00000073996 VEGA | MGI Sequence Detail 379 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000001642 G-protein coupled receptor 27
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
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  • All nucleic 5
    Genomic 1
    cDNA 3
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 20
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:45954 O'Dowd BF, et al., Discovery of three novel G-protein-coupled receptor genes. Genomics. 1998 Jan 15;47(2):310-3
  • Latest
    J:181489 Ku GM, et al., An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production. PLoS Genet. 2012 Jan;8(1):e1002449

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory