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Sec61g Gene Detail
Summary
  • Symbol
    Sec61g
  • Name
    SEC61, gamma subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202066
    NCBI Gene: 20335
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:16451638-16458484 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 9.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202066
protein coding gene Chr11:16450530-16458484 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018051
protein coding gene Chr11:13875914-13884660 (-)
A/J MGP_AJ_G0018024
protein coding gene Chr11:13404552-13412584 (-)
AKR/J MGP_AKRJ_G0017988
protein coding gene Chr11:13880694-13888648 (-)
BALB/cJ MGP_BALBcJ_G0017992
protein coding gene Chr11:13503249-13511537 (-)
C3H/HeJ MGP_C3HHeJ_G0017805
protein coding gene Chr11:13806785-13815987 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018444
protein coding gene Chr11:14463536-14471490 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016102
protein coding gene Chr11:12595435-12603288 (-)
CAST/EiJ MGP_CASTEiJ_G0017367
protein coding gene Chr11:13805372-13813285 (-)
CBA/J MGP_CBAJ_G0017780
protein coding gene Chr11:15278210-15286164 (-)
DBA/2J MGP_DBA2J_G0017890
protein coding gene Chr11:13386959-13394913 (-)
FVB/NJ MGP_FVBNJ_G0017882
protein coding gene Chr11:13186907-13194861 (-)
LP/J MGP_LPJ_G0017961
protein coding gene Chr11:14033043-14040986 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017908
protein coding gene Chr11:15710492-15718446 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018485
protein coding gene Chr11:13952618-13960561 (-)
PWK/PhJ MGP_PWKPhJ_G0017147
protein coding gene Chr11:13365496-13373607 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016944
protein coding gene Chr11:13728380-13736352 (-)
WSB/EiJ MGP_WSBEiJ_G0017421
protein coding gene Chr11:13657116-13665060 (-)



Homology
more
  • Human Ortholog
    SEC61G, SEC61 translocon subunit gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SEC61G, SEC61 translocon subunit gamma
  • Synonyms
    SSS1
  • Links
    NCBI Gene ID: 23480
    neXtProt AC: NX_P60059
    UniProt: P60059

  • Chr Location
    7p11.2; chr7:54752247-54759246 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20335 NCBI Gene Model | MGI Sequence Detail 6847 C57BL/6J ±  kb
transcript NM_001109971 RefSeq | MGI Sequence Detail 779 C57BL/6  
polypeptide P60060 UniProt | EBI | MGI Sequence Detail 68 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014598 protein transport protein Sec61 subunit gamma
  • InterPro Domains
    IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit
    IPR008158 Protein translocase SEC61 complex, gamma subunit
    IPR023391 Protein translocase SecE domain superfamily
Molecular
Reagents
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  • All nucleic 98
    cDNA 98

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:25193 Gordon HM, et al., Tumor necrosis factor induces genes involved in inflammation, cellular and tissue repair, and metabolism in murine fibroblasts. J Immunol. 1992 Jun 15;148(12):4021-7
  • Latest
    J:197701 Lang S, et al., Different effects of Sec61alpha, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci. 2012 Apr 15;125(Pt 8):1958-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory