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Pde1a
Gene Detail
 Symbol
Name
ID
Pde1a
phosphodiesterase 1A, calmodulin-dependent
MGI:1201792
Feature Type protein coding gene
Genetic Map
Chromosome 2
47.64 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:79834453-80129458 bp, - strand
From VEGA annotation of GRCm38

  295006 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21043  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 chicken; 1 zebrafish

Protein SuperFamily: 3',5'-cyclic-nucleotide phosphodiesterase 1B, calmodulin-dependent
Gene Tree: Pde1a

Human
homologs
Human Homolog PDE1A, phosphodiesterase 1A, calmodulin-dependent
NCBI Gene ID 5136
neXtProt AC  NX_P54750
Human Synonyms  CAM-PDE-1A, HCAM1, HCAM-1, HSPDE1A
Human Chr (Location)  2q32.1; chr2:182140035-182523380 (-)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cAMP catabolic process, cGMP catabolic process, ...
Component cytoplasm, neuronal cell body, ...
Function 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (249)    Tissues (155)    Images (35)
Theiler Stages: 10, 18, 22, 23, 25, 26, 28
Assay TypeResults
RNA in situ 237
Northern blot 12
cDNA source data(35)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(37) cDNA(36) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000013315 (Evidence)
Ensembl Gene ModelENSMUSG00000059173 (Evidence)
Entrez Gene18573 (Evidence)
UniGene40678
DFCITC1582978, TC1584306, TC1593308, TC1634389
DoTSDT.110667567, DT.110667575, DT.110667576, DT.40156711, DT.486104, DT.522384, DT.55282866, DT.91333704, DT.94263363
NIA Mouse Gene IndexU022795
EC3.1.4.17
Consensus CDS ProjectCCDS16172.1, CCDS16173.1, CCDS16174.1
International Mouse Knockout Project StatusPde1a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013315 VEGA Gene Model | MGI Sequence Detail 295006 C57BL/6J ±  kb
transcript OTTMUST00000032227 VEGA | MGI Sequence Detail 4258 Not Applicable 
polypeptide OTTMUSP00000014326 VEGA | MGI Sequence Detail 545 Not Applicable 

For the selected sequences
All sequences(95) RefSeq(20) UniProt(7)
Polymorphisms SNPs within 2kb(1475 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1477)
Protein-related
information
ResourceIDDescription
InterPro IPR023088 3'5'-cyclic nucleotide phosphodiesterase
InterPro IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
InterPro IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved site
InterPro IPR013706 3'5'-cyclic nucleotide phosphodiesterase N-terminal
InterPro IPR003607 HD/PDEase domain
Protein Ontology PR:000012466 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
References (Earliest) J:37553 Yan C, et al., Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9677-81
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(40)
Other
accession IDs
MGI:2139118, MGI:2139319

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory