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Tmprss15
Gene Detail
 Symbol
Name
ID
Tmprss15
transmembrane protease, serine 15
MGI:1197523
Synonyms A130097D21Rik, enterokinase, enteropeptidase, Prss7
Feature Type protein coding gene
Genetic Map
Chromosome 16
45.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:78953008-79091097 bp, - strand
From VEGA annotation of GRCm38

  138090 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2075  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: enteropeptidase
Gene Tree: Tmprss15

Human
homologs
Human Homolog TMPRSS15, transmembrane protease, serine 15
NCBI Gene ID 5651
neXtProt AC  NX_P98073
Human Synonyms  ENTK, PRSS7
Human Chr (Location)  21q21.1; chr21:18269116-18403653 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TMPRSS15
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Tmprss15 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tmprss15 interacts with 149 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process proteolysis
Component integral component of membrane, membrane
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (65)    Tissues (64)    Images (2)
Theiler Stages: 13, 15, 17, 20, 22, 23, 26, 27, 28
Assay TypeResults
RNA in situ 47
RT-PCR 18
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000025321 (Evidence)
Ensembl Gene ModelENSMUSG00000022857 (Evidence)
Entrez Gene19146 (Evidence)
UniGene5184
DFCITC1591924, TC1595802
DoTSDT.101344457, DT.55230525
NIA Mouse Gene IndexU037229
EC3.4.21.9
Consensus CDS ProjectCCDS28280.1, CCDS37380.1
International Mouse Knockout Project StatusTmprss15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025321 VEGA Gene Model | MGI Sequence Detail 138090 C57BL/6J ±  kb
transcript OTTMUST00000062326 VEGA | MGI Sequence Detail 4177 Not Applicable 
polypeptide OTTMUSP00000030708 VEGA | MGI Sequence Detail 1069 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(624 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR000859 CUB domain
InterPro IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
InterPro IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
InterPro IPR000998 MAM domain
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR011163 Peptidase S1A, enteropeptidase
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR000082 SEA domain
InterPro IPR001190 Speract/scavenger receptor
InterPro IPR017448 Speract/scavenger receptor-related
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000013329 enteropeptidase
References (Earliest) J:45786 Yuan X, et al., Structure of murine enterokinase (enteropeptidase) and expression in small intestine during development. Am J Physiol. 1998 Feb;274(2 Pt 1):G342-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:2442627

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory