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Tmprss15 Gene Detail
Summary
  • Symbol
    Tmprss15
  • Name
    transmembrane protease, serine 15
  • Synonyms
    A130097D21Rik, enterokinase, enteropeptidase, Prss7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1197523
    NCBI Gene: 19146
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:78953008-79091097 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 45.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    604 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1197523
protein coding gene Chr16:78953008-79091097 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022965
protein coding gene Chr16:79127238-79283952 (-)
A/J MGP_AJ_G0022933
protein coding gene Chr16:75641984-75774451 (-)
AKR/J MGP_AKRJ_G0022903
protein coding gene Chr16:77916867-78069616 (-)
BALB/cJ MGP_BALBcJ_G0022935
protein coding gene Chr16:76028745-76163683 (-)
C3H/HeJ MGP_C3HHeJ_G0022697
protein coding gene Chr16:78370589-78507120 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023382
protein coding gene Chr16:81675151-81821706 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020886
protein coding gene Chr16:74047840-74164394 (-)
CAST/EiJ MGP_CASTEiJ_G0022219
protein coding gene Chr16:78784644-78914018 (-)
CBA/J MGP_CBAJ_G0022666
protein coding gene Chr16:85165722-85320065 (-)
DBA/2J MGP_DBA2J_G0022800
protein coding gene Chr16:75474656-75606707 (-)
FVB/NJ MGP_FVBNJ_G0022775
protein coding gene Chr16:74816134-74960318 (-)
LP/J MGP_LPJ_G0022869
protein coding gene Chr16:78838772-78974095 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022794
protein coding gene Chr16:88373079-88541463 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023400
protein coding gene Chr16:78228345-78356364 (-)
PWK/PhJ MGP_PWKPhJ_G0021961
protein coding gene Chr16:75688369-75807382 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021791
protein coding gene Chr16:77922506-78046031 (-)
WSB/EiJ MGP_WSBEiJ_G0022267
protein coding gene Chr16:78495818-78633531 (-)



Homology
more
  • Human Ortholog
    TMPRSS15, transmembrane serine protease 15
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMPRSS15, transmembrane serine protease 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ENTK, PRSS7
  • Links
    NCBI Gene ID: 5651
    neXtProt AC: NX_P98073
    UniProt: P98073

  • Chr Location
    21q21.1; chr21:18269107-18403806 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19146 NCBI Gene Model | MGI Sequence Detail 138090 C57BL/6J ±  kb
    transcript NM_008941 RefSeq | MGI Sequence Detail 4194 C57BL/6  
    polypeptide P97435 UniProt | EBI | MGI Sequence Detail 1069 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 13
      Primer pair 3
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2442627
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:45786 Yuan X, et al., Structure of murine enterokinase (enteropeptidase) and expression in small intestine during development. Am J Physiol. 1998 Feb;274(2 Pt 1):G342-9
    • Latest
      J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory