Tmprss15
Gene Detail

Symbol Name ID

Tmprss15 transmembrane protease, serine 15 MGI:1197523

Synonyms

A130097D21Rik, enterokinase, enteropeptidase, Prss7

Feature Type

protein coding gene

Genetic Map

Chromosome 16

45.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr16:78953008-79091097 bp, - strand From VEGA annotation of GRCm38   138090 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2075  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: enteropeptidase
Gene Tree: Tmprss15

Human homologs

Human Homolog		TMPRSS15, transmembrane protease, serine 15
NCBI Gene ID		5651
neXtProt AC		NX_P98073
Human Synonyms		ENTK, PRSS7
Human Chr (Location)		21q21.1; chr21:19641433-19775970 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TMPRSS15

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	proteolysis
Component	integral to membrane, membrane
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (65)    Tissues (63)    Images (2)
Theiler Stages: 13, 15, 17, 20, 22, 23, 26, 28

Assay Type	Results
RNA in situ	47
RT-PCR	18

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000025321 (Evidence)
Ensembl Gene Model	ENSMUSG00000022857 (Evidence)
Entrez Gene	19146 (Evidence)
UniGene	5184
DFCI	TC1591924, TC1595802
DoTS	DT.101344457, DT.55230525
NIA Mouse Gene Index	U037229
EC	3.4.21.9
Consensus CDS Project	CCDS28280.1, CCDS37380.1
International Mouse Knockout Project Status	Tmprss15

Sequences

Length	Strain/Species
genomic	OTTMUSG00000025321	VEGA Gene Model | MGI Sequence Detail	138090	C57BL/6J
transcript	OTTMUST00000062326	VEGA | MGI Sequence Detail	4177	Not Applicable
polypeptide	OTTMUSP00000030708	VEGA | MGI Sequence Detail	1069	Not Applicable

All sequences(29) RefSeq(4) UniProt(4)

Polymorphisms

SNPs(518 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008985	Concanavalin A-like lectin/glucanases superfamily
InterPro	IPR000859	CUB domain
InterPro	IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site
InterPro	IPR002172	Low-density lipoprotein (LDL) receptor class A repeat
InterPro	IPR000998	MAM domain
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR011163	Peptidase S1A, enteropeptidase
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR000082	SEA domain
InterPro	IPR001190	Speract/scavenger receptor
InterPro	IPR017448	Speract/scavenger receptor-related
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000013329	enteropeptidase

References

(Earliest) J:45786 Yuan X, et al., Structure of murine enterokinase (enteropeptidase) and expression in small intestine during development. Am J Physiol. 1998 Feb;274(2 Pt 1):G342-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Other accession IDs

MGI:2442627