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Wnt9b
Gene Detail
 Symbol
Name
ID
Wnt9b
wingless-type MMTV integration site family, member 9B
MGI:1197020
Synonyms clf, clf1, Wnt14b, Wnt15
Feature Type protein coding gene
Genetic Map
Chromosome 11
67.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr11:103727364-103749821 bp, - strand
From VEGA annotation of GRCm38

  22458 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2551  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt9b

Human
homologs
Human Homolog WNT9B, wingless-type MMTV integration site family, member 9B
NCBI Gene ID 7484
neXtProt AC  NX_O14905
Human Synonyms  WNT14B, WNT15
Human Chr (Location)  17q21; chr17:46851586-46886730 (+)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Spontaneous(1) Targeted(5)
Incidental mutations (data from APF )
 
Homozygous null mice display neonatal lethality, disrupted ureteric bud branching, impaired Mullerian duct formation, and incompletely penetrant cleft lip and palate. In mice with alleles that decrease expression kidneys are smaller with fewer mature nephrons.
 
Phenotype Images(1)
Gene Ontology
(GO)
classifications
All GO classifications: (44 annotations)
Process branching involved in ureteric bud morphogenesis, branching morphogenesis of an epithelial tube, ...
Component extracellular region, extracellular space, ...
Function frizzled binding, receptor binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (76 records)
Data Summary: Results (558)    Tissues (452)    Images (38)
Theiler Stages: 1, 2, 3, 4, 5, 8, 9, 10, 11, 13, 15, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
RNA in situ 512
RT-PCR 44
RNase protection 2
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(36) Genomic(5) cDNA(18) Primer pair(10) Other(3)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000003017 (Evidence)
Ensembl Gene ModelENSMUSG00000018486 (Evidence)
Entrez Gene22412 (Evidence)
UniGene215161
DFCITC1588043, TC1642958
DoTSDT.87057942
Consensus CDS ProjectCCDS25522.1
International Mouse Knockout Project StatusWnt9b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003017 VEGA Gene Model | MGI Sequence Detail 22458 C57BL/6J ±  kb
transcript OTTMUST00000006192 VEGA | MGI Sequence Detail 4518 Not Applicable 
polypeptide OTTMUSP00000002922 VEGA | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms All PCR and RFLP(4) : PCR(2) RFLP(2) SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR026535 Wnt-9 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017453 protein Wnt-9b
References (Earliest) J:8487 Biddle FG, et al., Major gene determination of liability to spontaneous cleft lip in the mouse. J Craniofac Genet Dev Biol Suppl. 1986;2:67-88
(Latest) J:207612 Zhang L, et al., Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development. Dev Biol. 2014 Mar 1;387(1):64-72
All references(126)
Other
accession IDs
MGD-MRK-16443, MGD-MRK-2011, MGI:99658

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory