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Wnt9b Gene Detail
Summary
  • Symbol
    Wnt9b
  • Name
    wingless-type MMTV integration site family, member 9B
  • Synonyms
    clf, clf1, Wnt14b, Wnt15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1197020
    NCBI Gene: 22412
  • Gene Overview
    MyGene.info: WNT9B
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:103727364-103749821 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 67.47 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1197020
protein coding gene Chr11:103727363-103749821 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019268
protein coding gene Chr11:106831313-106853795 (-)
A/J MGP_AJ_G0019236
protein coding gene Chr11:102289462-102311924 (-)
AKR/J MGP_AKRJ_G0019205
protein coding gene Chr11:105433107-105455591 (-)
BALB/cJ MGP_BALBcJ_G0019210
protein coding gene Chr11:102728760-102751217 (-)
C3H/HeJ MGP_C3HHeJ_G0019019
protein coding gene Chr11:105663700-105686184 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019660
protein coding gene Chr11:110139416-110161873 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017285
protein coding gene Chr11:99702092-99724758 (-)
CAST/EiJ MGP_CASTEiJ_G0018573
protein coding gene Chr11:106681604-106704166 (-)
CBA/J MGP_CBAJ_G0018988
protein coding gene Chr11:114698161-114720620 (-)
DBA/2J MGP_DBA2J_G0019100
protein coding gene Chr11:101787413-101809897 (-)
FVB/NJ MGP_FVBNJ_G0019091
protein coding gene Chr11:101309961-101332418 (-)
LP/J MGP_LPJ_G0019169
protein coding gene Chr11:107319403-107341873 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019121
protein coding gene Chr11:114045882-114068339 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019697
protein coding gene Chr11:105817047-105839531 (-)
PWK/PhJ MGP_PWKPhJ_G0018337
protein coding gene Chr11:102868242-102892132 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018128
protein coding gene Chr11:105569868-105592456 (-)
WSB/EiJ MGP_WSBEiJ_G0018622
protein coding gene Chr11:105822079-105844553 (-)



Homology
more
  • Human Ortholog
    WNT9B, Wnt family member 9B
  • Vertebrate Orthologs
    11
  • Human Ortholog
    WNT9B, Wnt family member 9B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WNT14B, WNT15
  • Links
    NCBI Gene ID: 7484
    neXtProt AC: NX_O14905
    UniProt: O14905

  • Chr Location
    17q21.32; chr17:46833201-46886730 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    23 phenotypes from 4 alleles in 7 genetic backgrounds
    9 phenotypes from multigenic genotypes
    1 images
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice display neonatal lethality, disrupted ureteric bud branching, impaired Mullerian duct formation, and incompletely penetrant cleft lip and palate. In mice with alleles that decrease expression kidneys are smaller with fewer mature nephrons.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000018486 Ensembl Gene Model | MGI Sequence Detail 22458 C57BL/6J ±  kb
    transcript ENSMUST00000018630 Ensembl | MGI Sequence Detail 4518 Not Applicable  
    polypeptide ENSMUSP00000018630 Ensembl | MGI Sequence Detail 359 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 41
      Genomic 5
      cDNA 19
      Primer pair 11
      Other 6

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-16443, MGD-MRK-2011, MGI:99658
    References
    more
    • Summaries
      All 165
      Developmental Gene Expression 108
      Gene Ontology 13
      Phenotypes 27
    • Earliest
      J:8487 Biddle FG, et al., Major gene determination of liability to spontaneous cleft lip in the mouse. J Craniofac Genet Dev Biol Suppl. 1986;2:67-88
    • Latest
      J:264384 Ramalingam H, et al., Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 Aug 1;440(1):13-21

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory