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Wnt9b
Gene Detail
Symbol

Name
ID
Wnt9b
wingless-type MMTV integration site family, member 9B
MGI:1197020
Synonyms
clf, clf1, Wnt14b, Wnt15
Feature Type
protein coding gene
Genetic Map
Chromosome 11
67.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr11:103727364-103749821 bp, - strand
From VEGA annotation of GRCm38

  22458 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2551  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 1 zebrafish

HCOP human homology predictions: WNT9B
Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt9b

Human
homologs
WNT9B, wingless-type MMTV integration site family, member 9B
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7484
neXtProt AC: NX_O14905

Human Synonyms: WNT14B, WNT15

Human Chr (Location): 17q21.32; chr17:46833201-46886775 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Spontaneous(1) Targeted(6)
Genomic Mutations involving Wnt9b (1)
Incidental mutations (data from APF )
 
Homozygous null mice display neonatal lethality, disrupted ureteric bud branching, impaired Mullerian duct formation, and incompletely penetrant cleft lip and palate. In mice with alleles that decrease expression kidneys are smaller with fewer mature nephrons.
 
Phenotype Images(1)
Interactions
Wnt9b interacts with 316 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (84 records)
Data Summary: Results (554)    Tissues (449)    Images (38)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 512
RT-PCR 40
RNase protection 2
cDNA source data(18)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA WNT9B ; Xenbase wnt9b ; ZFIN wnt9b    NEW 
Molecular
reagents
All nucleic(36) Genomic(5) cDNA(18) Primer pair(10) Other(3)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000003017 (Evidence)
Ensembl Gene Model ENSMUSG00000018486 (Evidence)
Entrez Gene 22412 (Evidence)
UniGene 215161
DFCI TC1588043, TC1642958
DoTS DT.87057942
Consensus CDS Project CCDS25522.1
International Mouse Phenotyping Consortium Status Wnt9b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003017 VEGA Gene Model | MGI Sequence Detail 22458 C57BL/6J ±  kb
transcript OTTMUST00000006192 VEGA | MGI Sequence Detail 4518 Not Applicable 
polypeptide OTTMUSP00000002922 VEGA | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms
All PCR and RFLP(4) : PCR(2) RFLP(2) SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR026535 Wnt-9b protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017453 protein Wnt-9b
References
(Earliest) J:8487 Biddle FG, et al., Major gene determination of liability to spontaneous cleft lip in the mouse. J Craniofac Genet Dev Biol Suppl. 1986;2:67-88
(Latest) J:221164 Di Giovanni V, et al., Fibroblast growth factor receptor-Frs2alpha signaling is critical for nephron progenitors. Dev Biol. 2015 Apr 1;400(1):82-93
All references(133)
Other
accession IDs
MGD-MRK-16443, MGD-MRK-2011, MGI:99658

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory