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Kcns1
Gene Detail
Symbol

Name
ID
Kcns1
K+ voltage-gated channel, subfamily S, 1
MGI:1197019
Synonyms
Kv9.1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
84.60 cM, cytoband H3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:164163619-164171113 bp, - strand
From VEGA annotation of GRCm38

  7495 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20517  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KCNS1
Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns1

Human
homologs
KCNS1, potassium voltage-gated channel, modifier subfamily S, member 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 3787
neXtProt AC: NX_Q96KK3

Human Synonyms: KV9.1

Human Chr (Location): 20q12; chr20:45092072-45101112 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Kcns1 interacts with 100 markers (Mir10b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 3
cDNA source data(9)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(9) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000001173 (Evidence)
Ensembl Gene Model ENSMUSG00000040164 (Evidence)
Entrez Gene 16538 (Evidence)
UniGene 6217
DFCI TC1591964
DoTS DT.91332924, DT.101148938
Consensus CDS Project CCDS17022.1
International Mouse Phenotyping Consortium Status Kcns1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001173 VEGA Gene Model | MGI Sequence Detail 7495 C57BL/6J ±  kb
transcript OTTMUST00000002300 VEGA | MGI Sequence Detail 2712 Not Applicable 
polypeptide OTTMUSP00000001130 VEGA | MGI Sequence Detail 497 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003971 Potassium channel, voltage dependent, Kv9
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000798 voltage-gated potassium channel KCNS1
References
(Earliest) J:43210 Salinas M, et al., New modulatory alpha subunits for mammalian Shab K+ channels. J Biol Chem. 1997 Sep 26;272(39):24371-9
(Latest) J:119550 Harrell MD, et al., Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory