Kcns1
Gene Detail

Symbol Name ID

Kcns1 K+ voltage-gated channel, subfamily S, 1 MGI:1197019

Synonyms

Kv9.1

Feature Type

protein coding gene

Genetic Map

Chromosome 2

84.60 cM, cytoband H3
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr2:164163619-164171113 bp, - strand From VEGA annotation of GRCm38   7495 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:20517  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns1

Human homologs

Human Homolog		KCNS1, potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
NCBI Gene ID		3787
neXtProt AC		NX_Q96KK3
Human Synonyms		KV9.1
Human Chr (Location)		20q12; chr20:43720950-43729753 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (25 annotations)

Process	ion transmembrane transport, ion transport, ...
Component	integral to membrane, membrane, ...
Function	delayed rectifier potassium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (2)   
Theiler Stages: 25, 28

Assay Type	Results
RT-PCR	3

cDNA source data(9)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(11) cDNA(9) Primer pair(1) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000001173 (Evidence)
Ensembl Gene Model	ENSMUSG00000040164 (Evidence)
Entrez Gene	16538 (Evidence)
UniGene	6217
DFCI	TC1591964
DoTS	DT.101148938, DT.91332924
Consensus CDS Project	CCDS17022.1
International Mouse Knockout Project Status	Kcns1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000001173	VEGA Gene Model | MGI Sequence Detail	7495	C57BL/6J
transcript	OTTMUST00000002300	VEGA | MGI Sequence Detail	2712	Not Applicable
polypeptide	OTTMUSP00000001130	VEGA | MGI Sequence Detail	497	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(14 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR005821	Ion transport domain
InterPro	IPR003131	Potassium channel tetramerisation-type BTB domain
InterPro	IPR003968	Potassium channel, voltage dependent, Kv
InterPro	IPR003971	Potassium channel, voltage dependent, Kv9
InterPro	IPR003091	Voltage-dependent potassium channel
Protein Ontology	PR:000000798	voltage-gated potassium channel KCNS1

References

(Earliest) J:43210 Salinas M, et al., New modulatory alpha subunits for mammalian Shab K+ channels. J Biol Chem. 1997 Sep 26;272(39):24371-9
(Latest) J:119550 Harrell MD, et al., Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
All references(26)