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Kcns2 Gene Detail
Summary
  • Symbol
    Kcns2
  • Name
    K+ voltage-gated channel, subfamily S, 2
  • Synonyms
    E130006J24Rik, Kv9.2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1197011
    NCBI Gene: 16539
  • Gene Overview
    MyGene.info: KCNS2
Location & Maps
more
  • Sequence Map
    Chr15:34837381-34842337 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4957 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 14.34 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    KCNS2, potassium voltage-gated channel modifier subfamily S member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCNS2, potassium voltage-gated channel modifier subfamily S member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KV9.2
  • Links
    NCBI Gene ID: 3788
    neXtProt AC: NX_Q9ULS6

  • Chr Location
    8q22; chr8:98427022-98430797 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Targeted
    3
  • Genomic Mutations
    2 involving Kcns2
  • Incidental Mutations
Homozygous mutation of this gene results in no obvious phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050963 Ensembl Gene Model | MGI Sequence Detail 4957 C57BL/6J ±  kb
transcript ENSMUST00000072868 Ensembl | MGI Sequence Detail 4360 Not Applicable  
polypeptide ENSMUSP00000072645 Ensembl | MGI Sequence Detail 477 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    53 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000000799 voltage-gated potassium channel KCNS2
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR005821 Ion transport domain
    IPR013099 Potassium channel domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR003968 Potassium channel, voltage dependent, Kv
    IPR003971 Potassium channel, voltage dependent, Kv9
    IPR011333 SKP1/BTB/POZ domain
    IPR027359 Voltage-dependent channel, four helix bundle domain
    IPR028325 Voltage-gated potassium channel
Molecular
Reagents
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  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGI:2443152
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:43210 Salinas M, et al., New modulatory alpha subunits for mammalian Shab K+ channels. J Biol Chem. 1997 Sep 26;272(39):24371-9
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory