Kcns2
Gene Detail

Symbol Name ID

Kcns2 K+ voltage-gated channel, subfamily S, 2 MGI:1197011

Synonyms

E130006J24Rik, Kv9.2

Feature Type

protein coding gene

Genetic Map

Chromosome 15

14.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:34837381-34842337 bp, + strand From NCBI annotation of GRCm38   4957 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Kcns2 ± 2 cM)

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns2

Human ortholog

KCNS2 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 NCBI Gene ID 3788
Human Synonyms: KV9.2
Human Chr8:99439250-99443025 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Homozygous mutation of this gene results in no obvious phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (20 annotations)

Process	ion transport, potassium ion transmembrane transport, ...
Component	integral to membrane, membrane, ...
Function	delayed rectifier potassium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (4)    Images (9)
Theiler Stages: 23, 25, 28

Assay Type	Results
RNA in situ	11
RT-PCR	2

cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000050963 (Evidence)
Entrez Gene	16539 (Evidence)
DFCI	TC1586432, TC1610386
DoTS	DT.101725519, DT.94252064
NIA Mouse Gene Index	U016156
Consensus CDS Project	CCDS27421.1
International Mouse Knockout Project Status	Kcns2

Sequences

Length	Strain/Species
genomic	16539	NCBI Gene Model | MGI Sequence Detail	4957	C57BL/6J
transcript	NM_181317	RefSeq | MGI Sequence Detail	5473	Not Specified
polypeptide	O35174	UniProt | EBI | MGI Sequence Detail	477	Not Applicable

All sequences(28) RefSeq(4) UniProt(3)

Polymorphisms

SNPs(15 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR013099	Ion transport 2
InterPro	IPR005821	Ion transport domain
InterPro	IPR003131	Potassium channel tetramerisation-type BTB domain
InterPro	IPR003968	Potassium channel, voltage dependent, Kv
InterPro	IPR003971	Potassium channel, voltage dependent, Kv9
InterPro	IPR003091	Voltage-dependent potassium channel
Protein Ontology	PR:000000799	voltage-gated potassium channel KCNS2

Graphical View of Protein Domain Structure

References

(Earliest) J:43210 Salinas M, et al., New modulatory alpha subunits for mammalian Shab K+ channels. J Biol Chem. 1997 Sep 26;272(39):24371-9
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Other accession IDs

MGI:2443152