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Kcns2
Gene Detail
 Symbol
Name
ID
Kcns2
K+ voltage-gated channel, subfamily S, 2
MGI:1197011
Synonyms E130006J24Rik, Kv9.2
Feature Type protein coding gene
Genetic Map
Chromosome 15
14.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:34837381-34842337 bp, + strand
From NCBI annotation of GRCm38

  4957 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22465  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns2

Human
homologs
Human Homolog KCNS2, potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
NCBI Gene ID 3788
neXtProt AC  NX_Q9ULS6
Human Synonyms  KV9.2
Human Chr (Location)  8q22; chr8:98427022-98430797 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in no obvious phenotype.
 
Interactions
Kcns2 interacts with 363 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (4)    Images (9)
Theiler Stages: 23, 25, 27
Assay TypeResults
RNA in situ 11
RT-PCR 2
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000050963 (Evidence)
Entrez Gene16539 (Evidence)
DFCITC1586432, TC1610386
DoTSDT.101725519, DT.94252064
NIA Mouse Gene IndexU016156
Consensus CDS ProjectCCDS27421.1
International Mouse Knockout Project StatusKcns2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16539 NCBI Gene Model | MGI Sequence Detail 4957 C57BL/6J ±  kb
transcript NM_181317 RefSeq | MGI Sequence Detail 5473 Not Specified 
polypeptide O35174 UniProt | EBI | MGI Sequence Detail 477 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(53 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR013099 Ion transport 2
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003971 Potassium channel, voltage dependent, Kv9
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000799 voltage-gated potassium channel KCNS2
Graphical View of Protein Domain Structure
References (Earliest) J:43210 Salinas M, et al., New modulatory alpha subunits for mammalian Shab K+ channels. J Biol Chem. 1997 Sep 26;272(39):24371-9
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)
Other
accession IDs
MGI:2443152

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory