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Tcea3 Gene Detail
Summary
  • Symbol
    Tcea3
  • Name
    transcription elongation factor A (SII), 3
  • Synonyms
    S-II
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196908
    NCBI Gene: 21401
Location & Maps
more
  • Sequence Map
    Chr4:136247729-136274898 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27170 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 68.34 cM, cytoband D3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TCEA3, transcription elongation factor A3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TCEA3, transcription elongation factor A3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TFIIS, TFIIS.H
  • Links
    NCBI Gene ID: 6920
    neXtProt AC: NX_O75764

  • Chr Location
    1p36.12; chr1:23380909-23424779 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    70
  • Chemically induced (other)
    2
  • Gene trapped
    63
  • Targeted
    5
  • Genomic Mutations
    3 involving Tcea3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009868 VEGA Gene Model | MGI Sequence Detail 27170 C57BL/6J ±  kb
transcript OTTMUST00000022883 VEGA | MGI Sequence Detail 1251 Not Applicable  
polypeptide OTTMUSP00000010442 VEGA | MGI Sequence Detail 347 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    299 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016159 transcription elongation factor A protein 3
  • PDB
  • InterPro Domains
    IPR003618 Transcription elongation factor S-II, central domain
    IPR006289 Transcription elongation factor, TFIIS
    IPR003617 Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
    IPR016492 Transcription elongation factor, TFIIS-related
    IPR017923 Transcription factor IIS, N-terminal
    IPR001222 Zinc finger, TFIIS-type
Molecular
Reagents
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  • All nucleic 36
    cDNA 33
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:44380 Kanai A, et al., Heterogeneity and tissue-specific expression of eukaryotic transcription factor S-II-related protein mRNA. J Biochem. 1991 May;109(5):674-7
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory