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Mrpl23 Gene Detail
Summary
  • Symbol
    Mrpl23
  • Name
    mitochondrial ribosomal protein L23
  • Synonyms
    L23mrp, Rpl23l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196612
    NCBI Gene: 19935
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:142086423-142094484 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 87.95 cM
  • Mapping Data
    15 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196612
protein coding gene Chr7:142086423-142094484 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033260
protein coding gene Chr7:147792917-147800621 (+)
A/J MGP_AJ_G0033243
protein coding gene Chr7:143527323-143535027 (+)
AKR/J MGP_AKRJ_G0033175
protein coding gene Chr7:147553199-147561156 (+)
BALB/cJ MGP_BALBcJ_G0033244
protein coding gene Chr7:143297557-143305496 (+)
C3H/HeJ MGP_C3HHeJ_G0032959
protein coding gene Chr7:147313735-147323291 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033754
protein coding gene Chr7:153134259-153142036 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030727
protein coding gene Chr7:144734280-144742048 (+)
CAST/EiJ MGP_CASTEiJ_G0032282
protein coding gene Chr7:139624546-139632479 (+)
CBA/J MGP_CBAJ_G0032930
protein coding gene Chr7:158383895-158391843 (+)
DBA/2J MGP_DBA2J_G0033084
protein coding gene Chr7:141478492-141486428 (+)
FVB/NJ MGP_FVBNJ_G0033033
protein coding gene Chr7:141413460-141421583 (+)
LP/J MGP_LPJ_G0033177
protein coding gene Chr7:149302781-149310710 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033067
protein coding gene Chr7:159000063-159007705 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033773
protein coding gene Chr7:146501599-146510185 (+)
PWK/PhJ MGP_PWKPhJ_G0031990
protein coding gene Chr7:134806104-134814326 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031836
protein coding gene Chr7:133301423-133309359 (+)
WSB/EiJ MGP_WSBEiJ_G0032394
protein coding gene Chr7:147484298-147492238 (+)



Homology
more
  • Human Ortholog
    MRPL23, mitochondrial ribosomal protein L23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL23, mitochondrial ribosomal protein L23
  • Synonyms
    L23MRP, RPL23, RPL23L, uL23m
  • Links
    NCBI Gene ID: 6150
    neXtProt AC: NX_Q16540
    UniProt: Q16540

  • Chr Location
    11p15.5; chr11:1947278-2014944 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19935 NCBI Gene Model | MGI Sequence Detail 8062 C57BL/6J ±  kb
transcript NM_001417208 RefSeq | MGI Sequence Detail 654 ZRU/MplStud  
polypeptide O35972 UniProt | EBI | MGI Sequence Detail 146 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR013025 Large ribosomal subunit protein uL23-like
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR012678 Ribosomal protein uL23/eL15/eS24 core domain superfamily
Molecular
Reagents
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  • All nucleic 77
    Genomic 16
    cDNA 58
    Primer pair 3

    Microarray probesets 4
References
more
  • Summaries
    All 57
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 15
  • Earliest
    J:43998 Zubair M, et al., Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers. Genomics. 1997 Oct 15;45(2):290-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory