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Slc4a1ap Gene Detail
Summary
  • Symbol
    Slc4a1ap
  • Name
    solute carrier family 4 (anion exchanger), member 1, adaptor protein
  • Synonyms
    kanadaptin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196608
    NCBI Gene: 20534
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:31526995-31556932 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 17.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196608
protein coding gene Chr5:31526850-31558641 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029429
protein coding gene Chr5:29549304-29582307 (+)
A/J MGP_AJ_G0029395
protein coding gene Chr5:28600310-28630507 (+)
AKR/J MGP_AKRJ_G0029345
protein coding gene Chr5:29751201-29781299 (+)
BALB/cJ MGP_BALBcJ_G0029406
protein coding gene Chr5:29130724-29161168 (+)
C3H/HeJ MGP_C3HHeJ_G0029127
protein coding gene Chr5:29770766-29802630 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029859
protein coding gene Chr5:31376596-31406198 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027097
protein coding gene Chr5:26204696-26233764 (+)
CAST/EiJ MGP_CASTEiJ_G0028537
protein coding gene Chr5:28807001-28838939 (+)
CBA/J MGP_CBAJ_G0029095
protein coding gene Chr5:32007125-32040288 (+)
DBA/2J MGP_DBA2J_G0029244
protein coding gene Chr5:28760986-28791120 (+)
FVB/NJ MGP_FVBNJ_G0029202
protein coding gene Chr5:28181083-28210844 (+)
LP/J MGP_LPJ_G0029329
protein coding gene Chr5:30001184-30033011 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029231
protein coding gene Chr5:32834470-32868050 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029893
protein coding gene Chr5:29249079-29278858 (+)
PWK/PhJ MGP_PWKPhJ_G0028262
protein coding gene Chr5:27915526-27949446 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028093
protein coding gene Chr5:28712059-28743972 (+)
WSB/EiJ MGP_WSBEiJ_G0028618
protein coding gene Chr5:29318149-29350243 (+)



Homology
more
  • Human Ortholog
    SLC4A1AP, solute carrier family 4 member 1 adaptor protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC4A1AP, solute carrier family 4 member 1 adaptor protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HLC3
  • Links
    NCBI Gene ID: 22950
    neXtProt AC: NX_Q9BWU0
    UniProt: Q9BWU0

  • Chr Location
    2p23.3; chr2:27663471-27694980 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    5 involving Slc4a1ap
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029141 Ensembl Gene Model | MGI Sequence Detail 29938 C57BL/6J ±  kb
transcript ENSMUST00000202950 Ensembl | MGI Sequence Detail 2499 Not Applicable  
polypeptide ENSMUSP00000144257 Ensembl | MGI Sequence Detail 744 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    12 Sequences
  • InterPro Domains
    IPR000253 Forkhead-associated (FHA) domain
    IPR008984 SMAD/FHA domain superfamily
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 2
References
more
  • Summaries
    All 48
    Diseases 1
    Gene Ontology 3
    Phenotypes 27
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory