About   Help   FAQ
Adgre4 Gene Detail
Summary
  • Symbol
    Adgre4
  • Name
    adhesion G protein-coupled receptor E4
  • Synonyms
    D17Ertd479e, EGF-TM7, Emr4, FIRE, Gpr127
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196464
    NCBI Gene: 52614
Location & Maps
more
  • Sequence Map
    Chr17:55749984-55853662 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      103679 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 28.98 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ADGRE4P, adhesion G protein-coupled receptor E4, pseudogene
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ADGRE4P, adhesion G protein-coupled receptor E4, pseudogene
    Orthology source: HGNC
  • Synonyms
    EMR4, EMR4P, FIRE, GPR127, PGR16
  • Links
    NCBI Gene ID: 326342
    neXtProt AC: NX_Q86SQ3

  • Chr Location
    19p13.3; chr19:6952500-6990846 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52614 NCBI Gene Model | MGI Sequence Detail 103679 C57BL/6J ±  kb
transcript NM_139138 RefSeq | MGI Sequence Detail 3491 C57BL/6  
polypeptide Q91ZE5 UniProt | EBI | MGI Sequence Detail 689 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    132 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007289 EGF-like module-containing mucin-like hormone receptor-like 4
  • InterPro Domains
    IPR018097 EGF-like calcium-binding, conserved site
    IPR001881 EGF-like calcium-binding domain
    IPR001740 GPCR family 2, EMR1-like receptor
    IPR017981 GPCR, family 2-like
    IPR000832 GPCR, family 2, secretin-like
    IPR017983 GPCR, family 2, secretin-like, conserved site
    IPR000203 GPS motif
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:54030 Ring HZ, et al., Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17. Genomics. 1999 Mar 15;56(3):350-2
  • Latest
    J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory