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Adgre4 Gene Detail
Summary
  • Symbol
    Adgre4
  • Name
    adhesion G protein-coupled receptor E4
  • Synonyms
    D17Ertd479e, EGF-TM7, Emr4, FIRE, Gpr127
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196464
    NCBI Gene: 52614
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:55749984-55853662 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 28.98 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196464
protein coding gene Chr17:55749984-55853662 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023898
protein coding gene Chr17:57364663-57461792 (+)
A/J MGP_AJ_G0023858
protein coding gene Chr17:55817377-55909242 (+)
AKR/J MGP_AKRJ_G0023825
protein coding gene Chr17:56473649-56571811 (+)
BALB/cJ MGP_BALBcJ_G0023860
protein coding gene Chr17:55648376-55753003 (+)
C3H/HeJ MGP_C3HHeJ_G0023622
protein coding gene Chr17:57196123-57302929 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024303
protein coding gene Chr17:59632635-59738169 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021750
protein coding gene Chr17:52127709-52447499 (+)
CAST/EiJ MGP_CASTEiJ_G0023105
protein coding gene Chr17:57512963-57614586 (+)
CBA/J MGP_CBAJ_G0023599
protein coding gene Chr17:61922177-62033904 (+)
DBA/2J MGP_DBA2J_G0023727
protein coding gene Chr17:54548900-54648660 (+)
FVB/NJ MGP_FVBNJ_G0023693
protein coding gene Chr17:54073649-54170121 (+)
LP/J MGP_LPJ_G0023807
protein coding gene Chr17:58083721-58186576 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023721
protein coding gene Chr17:61469124-61590141 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024348
protein coding gene Chr17:56872570-56966557 (+)
PWK/PhJ MGP_PWKPhJ_G0022850
protein coding gene Chr17:53907886-54006376 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022662
protein coding gene Chr17:53633588-53728170 (+)
WSB/EiJ MGP_WSBEiJ_G0023169
protein coding gene Chr17:57487387-57581383 (+)



Homology
more
  • Human Ortholog
    ADGRE4P, adhesion G protein-coupled receptor E4, pseudogene
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ADGRE4P, adhesion G protein-coupled receptor E4, pseudogene
    Orthology source: HGNC
  • Synonyms
    EMR4, EMR4P, FIRE, GPR127, PGR16
  • Links
    NCBI Gene ID: 326342

  • Chr Location
    19p13.2; chr19:6952500-6990846 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52614 NCBI Gene Model | MGI Sequence Detail 103679 C57BL/6J ±  kb
transcript NM_139138 RefSeq | MGI Sequence Detail 3491 C57BL/6  
polypeptide Q91ZE5 UniProt | EBI | MGI Sequence Detail 689 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:54030 Ring HZ, et al., Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17. Genomics. 1999 Mar 15;56(3):350-2
  • Latest
    J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory