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Klhl7
Gene Detail
 Symbol
Name
ID
Klhl7
kelch-like 7
MGI:1196453
Synonyms 2700038B03Rik, D5Ertd363e, Klhl6, SBBI26
Feature Type protein coding gene
Genetic Map
Chromosome 5
10.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:24100590-24161223 bp, + strand
From Ensembl annotation of GRCm38

  60634 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10317  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: kelch-like protein, gigaxonin type
Gene Tree: Klhl7

Human
homologs
Human Homolog KLHL7, kelch-like family member 7
NCBI Gene ID 55975
neXtProt AC  NX_Q8IXQ5
Human Synonyms  KLHL6, SBBI26
Human Chr (Location)  7p15.3; chr7:23105734-23175421 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human KLHL7
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(15) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klhl7 interacts with 276 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process protein ubiquitination
Component Cul3-RING ubiquitin ligase complex, cytoplasm, ...
Function protein homodimerization activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (84)    Tissues (13)    Images (24)
Theiler Stages: 23
Assay TypeResults
RNA in situ 84
cDNA source data(64)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(65) cDNA(64) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000028986 (Evidence)
Entrez Gene52323 (Evidence)
UniGene273768
DFCITC1575340, TC1608910, TC1618799, TC1726518
DoTSDT.492774, DT.91595968, DT.97393407, DT.99840084
NIA Mouse Gene IndexU005355
Consensus CDS ProjectCCDS19114.1, CCDS51432.1
International Mouse Knockout Project StatusKlhl7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028986 Ensembl Gene Model | MGI Sequence Detail 60634 C57BL/6J ±  kb
transcript ENSMUST00000030841 Ensembl | MGI Sequence Detail 3419 Not Applicable 
polypeptide ENSMUSP00000030841 Ensembl | MGI Sequence Detail 586 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(527 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011705 BTB/Kelch-associated
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR015916 Galactose oxidase, beta-propeller
InterPro IPR017096 Kelch-like protein, gigaxonin
InterPro IPR006652 Kelch repeat type 1
InterPro IPR015915 Kelch-type beta propeller
Protein Ontology PR:000009403 kelch-like protein 7
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)
Other
accession IDs
MGI:1915157

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory