Klhl7
Gene Detail

Symbol Name ID

Klhl7 kelch-like 7 MGI:1196453

Synonyms

2700038B03Rik, D5Ertd363e, Klhl6, SBBI26

Feature Type

protein coding gene

Genetic Map

Chromosome 5

10.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr5:24100590-24161223 bp, + strand From Ensembl annotation of GRCm38   60634 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10317  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kelch-like protein, gigaxonin type
Gene Tree: Klhl7

Human homologs

Human Homolog		KLHL7, kelch-like family member 7
NCBI Gene ID		55975
neXtProt AC		NX_Q8IXQ5
Human Synonyms		KLHL6, SBBI26
Human Chr (Location)		7p15.3; chr7:23145353-23215040 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human KLHL7

Alleles and phenotypes

All alleles(17) : Targeted(2) Gene trapped(15)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	protein ubiquitination
Component	Cul3-RING ubiquitin ligase complex, cytoplasm, ...
Function	protein homodimerization activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (84)    Tissues (13)    Images (24)
Theiler Stages: 23

Assay Type	Results
RNA in situ	84

cDNA source data(65)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(66) cDNA(65) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000028986 (Evidence)
Entrez Gene	52323 (Evidence)
UniGene	273768
DFCI	TC1575340, TC1608910, TC1618799, TC1726518
DoTS	DT.492774, DT.91595968, DT.97393407, DT.99840084
NIA Mouse Gene Index	U005355
Consensus CDS Project	CCDS19114.1, CCDS51432.1
International Mouse Knockout Project Status	Klhl7

Sequences

Length	Strain/Species
genomic	ENSMUSG00000028986	Ensembl Gene Model | MGI Sequence Detail	60634	C57BL/6J
transcript	ENSMUST00000030841	Ensembl | MGI Sequence Detail	3419	Not Applicable
polypeptide	ENSMUSP00000030841	Ensembl | MGI Sequence Detail	586	Not Applicable

All sequences(33) RefSeq(4) UniProt(3)

Polymorphisms

SNPs(224 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011705	BTB/Kelch-associated
InterPro	IPR013069	BTB/POZ
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR017096	Kelch-like protein, gigaxonin
InterPro	IPR006652	Kelch repeat type 1
InterPro	IPR015915	Kelch-type beta propeller
Protein Ontology	PR:000009403	kelch-like protein 7

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)

Other accession IDs

MGI:1915157