Habp2
Gene Detail

Symbol Name ID

Habp2 hyaluronic acid binding protein 2 MGI:1196378

Synonyms

FSAP, MGC:28705

Feature Type

protein coding gene

Genetic Map

Chromosome 19

51.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:56287137-56320822 bp, + strand From VEGA annotation of GRCm38   33686 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3050  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: hyaluronan-binding protein 2
Gene Tree: Habp2

Human homologs

Human Homolog		HABP2, hyaluronan binding protein 2
NCBI Gene ID		3026
neXtProt AC		NX_Q14520
Human Synonyms		FSAP, HABP, HGFAL, PHBP
Human Chr (Location)		10q25.3; chr10:115310590-115349361 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human HABP2

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	proteolysis
Component	extracellular region
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (53)    Tissues (12)    Images (27)
Theiler Stages: 13, 19, 21, 22, 23, 26, 28

Assay Type	Results
RNA in situ	47
RT-PCR	6

cDNA source data(49)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(51) cDNA(49) Primer pair(2)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000036781 (Evidence)
Ensembl Gene Model	ENSMUSG00000025075 (Evidence)
Entrez Gene	226243 (Evidence)
UniGene	25791
DFCI	TC1585448, TC1719759
DoTS	DT.101371083, DT.530002, DT.87048700
NIA Mouse Gene Index	U019595
EC	3.4.21.-
Consensus CDS Project	CCDS50475.1
International Mouse Knockout Project Status	Habp2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000036781	VEGA Gene Model | MGI Sequence Detail	33686	C57BL/6J
transcript	OTTMUST00000094397	VEGA | MGI Sequence Detail	2314	Not Applicable
polypeptide	OTTMUSP00000052484	VEGA | MGI Sequence Detail	554	Not Applicable

All sequences(55) RefSeq(2) UniProt(8)

Polymorphisms

SNPs(153 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013032	EGF-like, conserved site
InterPro	IPR000742	Epidermal growth factor-like domain
InterPro	IPR000001	Kringle
InterPro	IPR018056	Kringle, conserved site
InterPro	IPR013806	Kringle-like fold
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000008428	hyaluronan-binding protein 2

References

(Earliest) J:44782 Hashimoto K, et al., Cloning of the cDNA for a mouse homologue of human PHBP: a novel hyaluronan-binding protein. Biol Pharm Bull. 1997 Nov;20(11):1127-30
(Latest) J:174611 Azhar M, et al., Transforming growth factor Beta2 is required for valve remodeling during heart development. Dev Dyn. 2011 Jul 20;
All references(32)

Other accession IDs

MGI:2147471