Agpat5
Gene Detail

Symbol Name ID

Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) MGI:1196345

Synonyms

1110013A05Rik, D8Ertd319e

Feature Type

protein coding gene

Genetic Map

Chromosome 8

10.30 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:18846277-18891361 bp, + strand From VEGA annotation of GRCm38   45085 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Agpat5 ± 2 cM)

Protein SuperFamily: 1-acyl-sn-glycerol-3-phosphate acyltransferase-like protein
Gene Tree: Agpat5

Human ortholog

AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 NCBI Gene ID 55326
Human Synonyms: 1AGPAT5, LPAATE
Human Chr8:6565878-6619024 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(34) : Targeted(2) Gene trapped(32)
 

Mice homozygous for disruptions in this gene display moderate fatty changes in the liver.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	acylglycerol metabolic process, lipid metabolic process, ...
Component	integral to membrane, membrane, ...
Function	1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (263)    Tissues (129)    Images (33)
Theiler Stages: 17, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	263

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000030978 (Evidence)
Ensembl Gene Model	ENSMUSG00000031467 (Evidence)
Entrez Gene	52123 (Evidence)
DFCI	TC1575334
EC	2.3.1.51
Consensus CDS Project	CCDS22126.1
International Mouse Knockout Project Status	Agpat5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030978	VEGA Gene Model | MGI Sequence Detail	45085	C57BL/6J
transcript	OTTMUST00000076712	VEGA | MGI Sequence Detail	10779	Not Applicable
polypeptide	OTTMUSP00000040427	VEGA | MGI Sequence Detail	365	Not Applicable

All sequences(37) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(16 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002123	Phospholipid/glycerol acyltransferase
Protein Ontology	PR:000003838	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)

Other accession IDs

MGI:1915880