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Agpat5
Gene Detail
Symbol

Name
ID
Agpat5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
MGI:1196345
Synonyms
1110013A05Rik, D8Ertd319e
Feature Type
protein coding gene
Genetic Map
Chromosome 8
10.30 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:18846277-18891361 bp, + strand
From VEGA annotation of GRCm38

  45085 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10153  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AGPAT5
Protein SuperFamily: 1-acyl-sn-glycerol-3-phosphate acyltransferase-like protein
Gene Tree: Agpat5

Human
homologs
AGPAT5, 1-acylglycerol-3-phosphate O-acyltransferase 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 55326
neXtProt AC: NX_Q9NUQ2

Human Synonyms: 1AGPAT5, LPAATE

Human Chr (Location): 8p23.1; chr8:6708357-6761503 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(32) Targeted(2)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for disruptions in this gene display moderate fatty changes in the liver.
 
Interactions
Agpat5 interacts with 535 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (263)    Tissues (130)    Images (33)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 263
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA AGPAT5 ; Xenbase agpat5    NEW 
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000030978 (Evidence)
Ensembl Gene Model ENSMUSG00000031467 (Evidence)
Entrez Gene 52123 (Evidence)
DFCI TC1575334
EC 2.3.1.51
Consensus CDS Project CCDS22126.1
International Mouse Phenotyping Consortium Status Agpat5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030978 VEGA Gene Model | MGI Sequence Detail 45085 C57BL/6J ±  kb
transcript OTTMUST00000076712 VEGA | MGI Sequence Detail 10779 Not Applicable 
polypeptide OTTMUSP00000040427 VEGA | MGI Sequence Detail 365 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(43 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002123 Phospholipid/glycerol acyltransferase
Protein Ontology PR:000003838 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
All references(36)
Other
accession IDs
MGI:1915880

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory