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Agpat5
Gene Detail
 Symbol
Name
ID
Agpat5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
MGI:1196345
Synonyms 1110013A05Rik, D8Ertd319e
Feature Type protein coding gene
Genetic Map
Chromosome 8
10.30 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:18846277-18891361 bp, + strand
From VEGA annotation of GRCm38

  45085 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10153  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: 1-acyl-sn-glycerol-3-phosphate acyltransferase-like protein
Gene Tree: Agpat5

Human
homologs
Human Homolog AGPAT5, 1-acylglycerol-3-phosphate O-acyltransferase 5
NCBI Gene ID 55326
neXtProt AC  NX_Q9NUQ2
Human Synonyms  1AGPAT5, LPAATE
Human Chr (Location)  8p23.1; chr8:6708357-6761503 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(32) Targeted(2)
Incidental mutations (data from APF )
 
Mice homozygous for disruptions in this gene display moderate fatty changes in the liver.
 
Interactions
Agpat5 interacts with 536 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process acylglycerol metabolic process, hematopoietic progenitor cell differentiation, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function 1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (263)    Tissues (129)    Images (33)
Theiler Stages: 17, 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 263
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000030978 (Evidence)
Ensembl Gene ModelENSMUSG00000031467 (Evidence)
Entrez Gene52123 (Evidence)
DFCITC1575334
EC2.3.1.51
Consensus CDS ProjectCCDS22126.1
International Mouse Knockout Project StatusAgpat5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030978 VEGA Gene Model | MGI Sequence Detail 45085 C57BL/6J ±  kb
transcript OTTMUST00000076712 VEGA | MGI Sequence Detail 10779 Not Applicable 
polypeptide OTTMUSP00000040427 VEGA | MGI Sequence Detail 365 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(43 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002123 Phospholipid/glycerol acyltransferase
Protein Ontology PR:000003838 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
All references(37)
Other
accession IDs
MGI:1915880

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory