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Tcaim Gene Detail
Summary
  • Symbol
    Tcaim
  • Name
    T cell activation inhibitor, mitochondrial
  • Synonyms
    D9Ertd402e, LOC382117
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196217
    NCBI Gene: 382117
  • Gene Overview
    MyGene.info: TCAIM
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:122805539-122836334 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 73.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196217
protein coding gene Chr9:122805357-122838924 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035462
protein coding gene Chr9:125806299-125837006 (+)
A/J MGP_AJ_G0035443
protein coding gene Chr9:120993334-121023944 (+)
AKR/J MGP_AKRJ_G0035376
protein coding gene Chr9:124246295-124276863 (+)
BALB/cJ MGP_BALBcJ_G0035439
protein coding gene Chr9:120915133-120945293 (+)
C3H/HeJ MGP_C3HHeJ_G0035146
protein coding gene Chr9:124681280-124717308 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035962
protein coding gene Chr9:129264917-129310351 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032844
protein coding gene Chr9:118121563-118158450 (+)
CAST/EiJ MGP_CASTEiJ_G0034451
protein coding gene Chr9:124708363-124744455 (+)
CBA/J MGP_CBAJ_G0035114
protein coding gene Chr9:133990931-134023143 (+)
DBA/2J MGP_DBA2J_G0035273
protein coding gene Chr9:120441802-120473370 (+)
FVB/NJ MGP_FVBNJ_G0035220
protein coding gene Chr9:119360876-119392367 (+)
LP/J MGP_LPJ_G0035352
protein coding gene Chr9:126146801-126178083 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035261
protein coding gene Chr9:134851709-134886291 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035981
protein coding gene Chr9:124700906-124731531 (+)
PWK/PhJ MGP_PWKPhJ_G0034155
protein coding gene Chr9:120897126-120929040 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033992
protein coding gene Chr9:124784373-124820485 (+)
WSB/EiJ MGP_WSBEiJ_G0034571
protein coding gene Chr9:124545055-124577374 (+)



Homology
more
  • Human Ortholog
    TCAIM, T cell activation inhibitor, mitochondrial
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TCAIM, T cell activation inhibitor, mitochondrial
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C3orf23, TOAG1, TOAG-1
  • Links
    NCBI Gene ID: 285343
    neXtProt AC: NX_Q8N3R3
    UniProt: Q8N3R3

  • Chr Location
    3p21.31; chr3:44338119-44409448 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 45481
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TCAIM
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046603 Ensembl Gene Model | MGI Sequence Detail 30796 C57BL/6J ±  kb
transcript ENSMUST00000052740 Ensembl | MGI Sequence Detail 3049 Not Applicable  
polypeptide ENSMUSP00000049759 Ensembl | MGI Sequence Detail 509 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR028031 Domain of unknown function DUF4460
    IPR027989 Domain of unknown function DUF4461
    IPR027986 T-cell activation inhibitor, mitochondrial
Molecular
Reagents
less
  • All nucleic 32
    cDNA 31
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685975
References
more
  • Summaries
    All 30
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory