About   Help   FAQ
Elovl3
Gene Detail
Symbol

Name
ID
Elovl3
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
MGI:1195976
Synonyms
Cig30, CIN-2
Feature Type
protein coding gene
Genetic Map
Chromosome 19
38.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr19:46131897-46135307 bp, + strand
From VEGA annotation of GRCm38

  3411 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Elovl3

Human
homologs
Human Homolog ELOVL3, ELOVL fatty acid elongase 3
NCBI Gene ID 83401
neXtProt AC  NX_Q9HB03
Human Synonyms  CIG30, CIG-30
Human Chr (Location)  10q24.32; chr10:102226278-102229589 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Genomic Mutations involving Elovl3 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutants have a sparse coat, hyperplastic pilosebaceous system, and abnormal hair lipid content with high levels of eicosenoic acid. Liver and brown adipose tissue functions are normal.
 
Phenotype Images(4)
Interactions
Elovl3 interacts with 130 markers (Mir1b, Mir17, Mir20b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (13 records)
Data Summary: Results (20)    Tissues (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 20
cDNA source data(32)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(36) Genomic(1) cDNA(33) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023197 (Evidence)
Ensembl Gene ModelENSMUSG00000038754 (Evidence)
Entrez Gene12686 (Evidence)
UniGene21806
NIA Mouse Gene IndexU019519
EC2.3.1.199
Consensus CDS ProjectCCDS29871.1
International Mouse Knockout Project StatusElovl3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023197 VEGA Gene Model | MGI Sequence Detail 3411 C57BL/6J ±  kb
transcript OTTMUST00000056120 VEGA | MGI Sequence Detail 1494 Not Applicable 
polypeptide OTTMUSP00000026930 VEGA | MGI Sequence Detail 271 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002076 GNS1/SUR4 membrane protein
Protein Ontology PR:000007038 elongation of very long chain fatty acids protein 3
References
(Earliest) J:8101 Jacobsson A, et al., Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression. J Biol Chem. 1985 Dec 25;260(30):16250-4
(Latest) J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory