Homozygous mutants have dry eyes, poor postweaning growth associated with impaired parasympathetic cholinergic innervation of lacrimal and salivary glands and of small intestine, reduced skin thickness and accelerated hair follicle regression.
|Process||cytokine-mediated signaling pathway, glial cell-derived neurotrophic factor receptor signaling pathway, ...|
|Component||anchored component of membrane, membrane, ...|
|Function||glial cell-derived neurotrophic factor receptor activity, receptor activity|
|RNA in situ||67|
|InterPro||IPR003438||Glial cell line-derived neurotrophic factor receptor|
|InterPro||IPR017372||Glial cell line-derived neurotrophic factor receptor, alpha 1/2|
|InterPro||IPR003504||Glial cell line-derived neurotrophic factor receptor alpha 2|
|Protein Ontology||PR:000007949||GDNF family receptor alpha-2|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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