About   Help   FAQ
Abce1 Gene Detail
Summary
  • Symbol
    Abce1
  • Name
    ATP-binding cassette, sub-family E (OABP), member 1
  • Synonyms
    Oabp, Rnaseli, RNS4l (Eye)
  • Feature Type
    protein coding gene
  • IDs
    MGI:1195458
    NCBI Gene: 24015
Location & Maps
more
  • Sequence Map
    Chr8:79683442-79711740 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28299 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ABCE1, ATP binding cassette subfamily E member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ABCE1, ATP binding cassette subfamily E member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
  • Links
    NCBI Gene ID: 6059
    neXtProt AC: NX_P61221

  • Chr Location
    4q31; chr4:145098004-145129524 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2205
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ABCE1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    14 phenotype references
  • All Mutations and Alleles
    51
  • Chemically induced (other)
    1
  • Gene trapped
    45
  • Targeted
    4
  • Transgenic
    1
  • Genomic Mutations
    1 involving Abce1
  • Incidental Mutations
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 24015 NCBI Gene Model | MGI Sequence Detail 28299 C57BL/6J ±  kb
transcript NM_015751 RefSeq | MGI Sequence Detail 3813 C57BL/6  
polypeptide P61222 UniProt | EBI | MGI Sequence Detail 599 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    127 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000003568 ATP-binding cassette sub-family E member 1
  • InterPro Domains
    IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
    IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain
    IPR003593 AAA+ ATPase domain
    IPR013283 ABC transporter ABCE
    IPR017871 ABC transporter, conserved site
    IPR003439 ABC transporter-like
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR007209 RNase L inhibitor RLI, possible metal-binding domain
Molecular
Reagents
less
  • All nucleic 285
    cDNA 284
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139480
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:41448 Semsei I, et al., Expression of mRNAs of pancreatic and L type RNase inhibitors as a function of age in different tissues of SAMP8 and BDF1 mice. Mech Ageing Dev. 1997 Sep;97(3):249-61
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory