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Rnh1 Gene Detail
Summary
  • Symbol
    Rnh1
  • Name
    ribonuclease/angiogenin inhibitor 1
  • Synonyms
    RNH
  • Feature Type
    protein coding gene
  • IDs
    MGI:1195456
    NCBI Gene: 107702
  • Gene Overview
    MyGene.info: RNH1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141160326-141172851 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 86.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1195456
protein coding gene Chr7:141160326-141172857 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033213
protein coding gene Chr7:146334828-146347351 (-)
A/J MGP_AJ_G0033195
protein coding gene Chr7:142151493-142164016 (-)
AKR/J MGP_AKRJ_G0033127
protein coding gene Chr7:146068263-146080771 (-)
BALB/cJ MGP_BALBcJ_G0033196
protein coding gene Chr7:141892055-141904574 (-)
C3H/HeJ MGP_C3HHeJ_G0032910
protein coding gene Chr7:145822279-145835718 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033707
protein coding gene Chr7:151684820-151698677 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030680
protein coding gene Chr7:143359875-143372478 (-)
CAST/EiJ MGP_CASTEiJ_G0032240
protein coding gene Chr7:138127993-138140593 (-)
CBA/J MGP_CBAJ_G0032882
protein coding gene Chr7:156795204-156807683 (-)
DBA/2J MGP_DBA2J_G0033034
protein coding gene Chr7:140098585-140111133 (-)
FVB/NJ MGP_FVBNJ_G0032987
protein coding gene Chr7:140007243-140020672 (-)
LP/J MGP_LPJ_G0033129
protein coding gene Chr7:147824614-147837137 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033020
protein coding gene Chr7:157477834-157490429 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033727
protein coding gene Chr7:145047236-145059759 (-)
PWK/PhJ MGP_PWKPhJ_G0031944
protein coding gene Chr7:133376220-133389219 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031791
protein coding gene Chr7:131864358-131879917 (-)
WSB/EiJ MGP_WSBEiJ_G0032351
protein coding gene Chr7:145994448-146006889 (-)



Homology
more
  • Human Ortholog
    RNH1, ribonuclease/angiogenin inhibitor 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RNH1, ribonuclease/angiogenin inhibitor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RAI, RNH
  • Links
    NCBI Gene ID: 6050
    neXtProt AC: NX_P13489
    UniProt: P13489

  • Chr Location
    11p15.5; chr11:494512-507283 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 107702 NCBI Gene Model | MGI Sequence Detail 12526 C57BL/6J ±  kb
transcript NM_145135 RefSeq | MGI Sequence Detail 1807 C57BL/6  
polypeptide Q91VI7 UniProt | EBI | MGI Sequence Detail 456 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • PDB
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
Molecular
Reagents
less
  • All nucleic 260
    cDNA 260

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142254, MGI:2142343
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:41448 Semsei I, et al., Expression of mRNAs of pancreatic and L type RNase inhibitors as a function of age in different tissues of SAMP8 and BDF1 mice. Mech Ageing Dev. 1997 Sep;97(3):249-61
  • Latest
    J:261784 Chennupati V, et al., Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018 Apr 2;128(4):1597-1614

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory