Bloc1s1
Gene Detail

Symbol Name ID

Bloc1s1 biogenesis of lysosome-related organelles complex-1, subunit 1 MGI:1195276

Synonyms

BLOS1, Gcn5l1

Feature Type

protein coding gene

Genetic Map

Chromosome 10

77.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr10:128917882-128924035 bp, - strand From VEGA annotation of GRCm38   6154 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1140  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: biogenesis of lysosome-related organelles complex-1 subunit 1
Gene Tree: Bloc1s1

Human homologs

Human Homolog		BLOC1S1, biogenesis of lysosomal organelles complex-1, subunit 1
NCBI Gene ID		2647
neXtProt AC		NX_P78537
Human Synonyms		BLOS1, GCN5L1, MICoA, RT14
Human Chr (Location)		12q13-q14; chr12:56109818-56113491 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	aerobic respiration, anterograde axon cargo transport, ...
Component	BLOC-1 complex, cytoplasm, ...
Function	protein binding

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

cDNA source data(97)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(102) Genomic(4) cDNA(98)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000033474 (Evidence)
Ensembl Gene Model	ENSMUSG00000090247 (Evidence)
Entrez Gene	14533 (Evidence)
UniGene	30118
DFCI	TC1578444
DoTS	DT.101285241, DT.110748072, DT.494534
Consensus CDS Project	CCDS24299.1
International Mouse Knockout Project Status	Bloc1s1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000033474	VEGA Gene Model | MGI Sequence Detail	6154	C57BL/6J
transcript	OTTMUST00000084120	VEGA | MGI Sequence Detail	550	Not Applicable
polypeptide	OTTMUSP00000045287	VEGA | MGI Sequence Detail	125	Not Applicable

All sequences(37) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(6 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009395	GCN5-like 1
Protein Ontology	PR:000004762	biogenesis of lysosome-related organelles complex 1 subunit 1

References

(Earliest) J:44704 Driessen CA, et al., Cloning and structural analysis of the murine GCN5L1 gene. Gene. 1997 Dec 5;203(1):27-31
(Latest) J:192646 Yang Q, et al., The BLOS1-interacting protein KXD1 is involved in the biogenesis of lysosome-related organelles. Traffic. 2012 Aug;13(8):1160-9
All references(36)

Other accession IDs

MGI:2147264