Rdh1
Gene Detail

Symbol Name ID

Rdh1 retinol dehydrogenase 1 (all trans) MGI:1195275

Feature Type

protein coding gene

Genetic Map

Chromosome 10

75.21 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr10:127759721-127768297 bp, + strand From VEGA annotation of GRCm38   8577 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:74505  Vertebrate Homology Class
5 mouse; 1 rat; 1 zebrafish

Protein SuperFamily: retinol dehydrogenase
Gene Tree: Rdh1

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for a null allele exhibit increased body weight, adipose tissue, and retinol levels.

 

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	oxidation-reduction process, retinoid metabolic process, ...
Function	retinol dehydrogenase activity, steroid dehydrogenase activity

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (4)    Tissues (4)    Images (1)
Theiler Stages: 9, 11, 13, 15

Assay Type	Results
RT-PCR	4

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000027662 (Evidence)
Ensembl Gene Model	ENSMUSG00000089789 (Evidence)
Entrez Gene	107605 (Evidence)
UniGene	484271
DFCI	TC1599785
DoTS	DT.97394999
NIA Mouse Gene Index	U335256
Consensus CDS Project	CCDS24250.1
International Mouse Knockout Project Status	Rdh1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027662	VEGA Gene Model | MGI Sequence Detail	8577	C57BL/6J
transcript	OTTMUST00000068444	VEGA | MGI Sequence Detail	3930	Not Applicable
polypeptide	OTTMUSP00000034612	VEGA | MGI Sequence Detail	317	Not Applicable

All sequences(18) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(65 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002347	Glucose/ribitol dehydrogenase
InterPro	IPR016040	NAD(P)-binding domain
InterPro	IPR020904	Short-chain dehydrogenase/reductase, conserved site
InterPro	IPR002198	Short-chain dehydrogenase/reductase SDR

References

(Earliest) J:44704 Driessen CA, et al., Cloning and structural analysis of the murine GCN5L1 gene. Gene. 1997 Dec 5;203(1):27-31
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)