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Fxyd2
Gene Detail
Symbol

Name
ID
Fxyd2
FXYD domain-containing ion transport regulator 2
MGI:1195260
Synonyms
Atp1g1
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:45403138-45410278 bp, + strand
From Ensembl annotation of GRCm38

  7141 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Fxyd2
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
 
Homozygous null mice are viable and fertile but display abnormal renal NaK-ATPase kinetics.
 
Interactions
Fxyd2 interacts with 35 markers (Mir23a, Mir34a, Mir34b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (130)    Tissues (73)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 73
RT-PCR 57
cDNA source data(193)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fxyd2    NEW 
Molecular
reagents
All nucleic(197) cDNA(194) Primer pair(3)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000059412 (Evidence)
Entrez Gene 11936 (Evidence)
UniGene 22742
DFCI TC1575324, TC1581940, TC1627336, TC1640686
DoTS DT.101240087, DT.101272173, DT.101355523, DT.101375757, DT.536389, DT.94380982
NIA Mouse Gene Index U010415
Consensus CDS Project CCDS23134.1
International Mouse Phenotyping Consortium Status Fxyd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059412 Ensembl Gene Model | MGI Sequence Detail 7141 C57BL/6J ±  kb
transcript ENSMUST00000041005 Ensembl | MGI Sequence Detail 632 Not Applicable 
polypeptide ENSMUSP00000035429 Ensembl | MGI Sequence Detail 64 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(5) UniProt(4)
Polymorphisms
SNPs within 2kb(167 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000272 Ion-transport regulator, FXYD motif
Protein Ontology PR:000007714 sodium/potassium-transporting ATPase subunit gamma
References
(Earliest) J:39176 Mercer RW, et al., Molecular cloning and immunological characterization of the gamma polypeptide, a small protein associated with the Na,K-ATPase. J Cell Biol. 1993 May;121(3):579-86
(Latest) J:196889 Arystarkhova E, et al., Hyperplasia of pancreatic beta cells and improved glucose tolerance in mice deficient in the FXYD2 subunit of Na,K-ATPase. J Biol Chem. 2013 Mar 8;288(10):7077-85
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory